ICD-10-CM 2027
ICD-10 code for syphilis exposure
Contact with and (suspected) exposure to infections with a predominantly sexual mode of transmission
From the official ICD-10-CM alphabetic index entry “Exposure (to) › syphilis”. Page updated September 29, 2026.
About coding syphilis exposure
The ICD-10-CM code for syphilis exposure is Z20.2 (Contact with and (suspected) exposure to infections with a predominantly sexual mode of transmission).
Within Z20 (contact with and (suspected) exposure to communicable diseases), Z20.2 is specifically for contact with and (suspected) exposure to infections with a predominantly sexual mode of transmission. Related codes cover intestinal infectious diseases (Z20.0), tuberculosis (Z20.1), rabies (Z20.3), rubella (Z20.4), viral hepatitis (Z20.5), human immunodeficiency virus [HIV] (Z20.6), pediculosis, acariasis and other infestations (Z20.7), other communicable diseases (Z20.8) and 1 more.
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 795 (Normal Newborn, relative weight 0.2022) and DRG 951 (Other Factors Influencing Health Status, relative weight 0.5577), in MDC 15 (Newborns and Other Neonates with Conditions Originating in the Perinatal Period) and MDC 23 (Factors Influencing Health Status and Other Contacts with Health Services), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
Common questions about syphilis exposure ICD-10 codes
What is the ICD-10 code for syphilis exposure?
- Z20.2 — Contact with and (suspected) exposure to infections with a predominantly sexual mode of transmission.
Is Z20.2 billable?
- Yes. Z20.2 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can Z20.2 be used as a principal diagnosis?
- No. It is not acceptable as the principal diagnosis for an inpatient stay; it may be reported as a secondary diagnosis.
Is Z20.2 a CC or MCC?
- No. Z20.2 is neither a CC nor an MCC under MS-DRG v44.0.