ICD-10-CM 2027
ICD-10 code for syphilis screening
Encounter for screening for infections with a predominantly sexual mode of transmission
From the official ICD-10-CM alphabetic index entry “Screening (for) › syphilis”. Page updated September 29, 2026.
About coding syphilis screening
The ICD-10-CM code for syphilis screening is Z11.3 (Encounter for screening for infections with a predominantly sexual mode of transmission).
Within Z11 (encounter for screening for infectious and parasitic diseases), Z11.3 is specifically for encounter for screening for infections with a predominantly sexual mode of transmission. Related codes cover screening for intestinal infectious diseases (Z11.0), screening for respiratory tuberculosis (Z11.1), screening for other bacterial diseases (Z11.2), screening for human immunodeficiency virus [HIV] (Z11.4), screening for other viral diseases (Z11.5), screening for other protozoal diseases and helminthiases (Z11.6), testing for latent tuberculosis infection (Z11.7), screening for other infectious and parasitic diseases (Z11.8) and 1 more.
The conditions in its Excludes2 note aren't part of Z11.3, but may be coded alongside it if the patient has both: encounter for screening for human immunodeficiency virus [HIV] (Z11.4) and encounter for screening for human papillomavirus (Z11.51).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
Common questions about syphilis screening ICD-10 codes
What is the ICD-10 code for syphilis screening?
- Z11.3 — Encounter for screening for infections with a predominantly sexual mode of transmission.
Is Z11.3 billable?
- Yes. Z11.3 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can Z11.3 be used as a principal diagnosis?
- No. It is not acceptable as the principal diagnosis for an inpatient stay; it may be reported as a secondary diagnosis.
Is Z11.3 a CC or MCC?
- No. Z11.3 is neither a CC nor an MCC under MS-DRG v44.0.