Skip to content
Dx

ICD-10-CM 2027

ICD-10 code for syphilitic lymphadenitis

A51.49

Other secondary syphilitic conditions

✓ Billable / specificCC — complication/comorbidity

From the official ICD-10-CM alphabetic index entry “Lymphadenitis › syphilitic (early) (secondary)”. Page updated September 29, 2026.

About coding syphilitic lymphadenitis

The ICD-10-CM code for syphilitic lymphadenitis is A51.49 (Other secondary syphilitic conditions). The official index lists 1 more specific code, so check the documentation for details such as type, cause, site or severity before settling on A51.49.

Within A51.4, choose A51.49 (Other secondary syphilitic conditions) only when documentation doesn't support a more specific option: secondary syphilitic meningitis (A51.41), secondary syphilitic female pelvic disease (A51.42), secondary syphilitic oculopathy (A51.43), secondary syphilitic nephritis (A51.44), secondary syphilitic hepatitis (A51.45) and secondary syphilitic osteopathy (A51.46).

As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.

In MS-DRG v44.0, it is part of the grouping logic for DRG 867 (Other Infectious and Parasitic Diseases Diagnoses with MCC, relative weight 2.1859), DRG 868 (Other Infectious and Parasitic Diseases Diagnoses with CC, relative weight 1.0235) and DRG 869 (Other Infectious and Parasitic Diseases Diagnoses without CC/MCC, relative weight 0.6787), in MDC 18 (Infectious and Parasitic Diseases, Systemic or Unspecified Sites), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

More specific syphilitic lymphadenitis codes (official index)

  • late A52.79 — Other symptomatic late syphilis

Common questions about syphilitic lymphadenitis ICD-10 codes

What is the ICD-10 code for syphilitic lymphadenitis?

A51.49 — Other secondary syphilitic conditions. More specific codes apply when the documentation supports them: A52.79.

What is the ICD-10 code for late syphilitic lymphadenitis?

A52.79 — Other symptomatic late syphilis.

Is A51.49 billable?

Yes. A51.49 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can A51.49 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict A51.49 as a principal diagnosis.

Is A51.49 a CC or MCC?

A51.49 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.