ICD-10-CM 2027
ICD-10 code for toxic shock syndrome
From the official ICD-10-CM alphabetic index entry “Syndrome › toxic shock”. Page updated September 29, 2026.
About coding toxic shock syndrome
The ICD-10-CM code for toxic shock syndrome is A48.3 (Toxic shock syndrome).
Within A48 (other bacterial diseases, not elsewhere classified), A48.3 is specifically for toxic shock syndrome. Related codes cover gas gangrene (A48.0), Legionnaires' disease (A48.1), Nonpneumonic Legionnaires' disease [Pontiac fever] (A48.2), Brazilian purpuric fever (A48.4), other specified botulism (A48.5) and other specified bacterial diseases (A48.8).
Don't report A48.3 together with the conditions in its Excludes1 note: endotoxic shock NOS (R57.8) and sepsis NOS (A41.9).
Don't confuse with (Excludes1 for A48.3)
Common questions about toxic shock syndrome ICD-10 codes
What is the ICD-10 code for toxic shock syndrome?
- A48.3 — Toxic shock syndrome.
Is A48.3 billable?
- Yes. A48.3 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can A48.3 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict A48.3 as a principal diagnosis.
Is A48.3 a CC or MCC?
- A48.3 is an MCC (major complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.