ICD-10-CM 2027
ICD-10 code for vera polycythemia
From the official ICD-10-CM alphabetic index entry “Polycythemia (secondary) › vera”. Page updated September 29, 2026.
About coding vera polycythemia
The ICD-10-CM code for vera polycythemia is D45 (Polycythemia vera).
Don't report D45 together with the conditions in its Excludes1 note: familial polycythemia (D75.0) and secondary polycythemia (D75.1).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 820 (Lymphoma and Leukemia with Major O.R. Procedures with MCC, relative weight 6.2481), DRG 821 (Lymphoma and Leukemia with Major O.R. Procedures with CC, relative weight 2.2023), DRG 822 (Lymphoma and Leukemia with Major O.R. Procedures without CC/MCC, relative weight 1.1272), DRG 823 (Lymphoma and Non-Acute Leukemia with Other Procedures with MCC, relative weight 4.6059), DRG 824 (Lymphoma and Non-Acute Leukemia with Other Procedures with CC, relative weight 2.2515), DRG 825 (Lymphoma and Non-Acute Leukemia with Other Procedures without CC/MCC, relative weight 1.2995) and 3 more, in MDC 17 (Myeloproliferative Diseases and Disorders, Poorly Differentiated Neoplasms), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
Don't confuse with (Excludes1 for D45)
Common questions about vera polycythemia ICD-10 codes
What is the ICD-10 code for vera polycythemia?
- D45 — Polycythemia vera.
Is D45 billable?
- Yes. D45 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can D45 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict D45 as a principal diagnosis.
Is D45 a CC or MCC?
- No. D45 is neither a CC nor an MCC under MS-DRG v44.0.