ICD-10-CM 2027
ICD-10 code for vertebra osteomyelitis
Osteomyelitis of vertebra, site unspecified
From the official ICD-10-CM alphabetic index entry “Osteomyelitis (general) (infective) (localized) (neonatal) (purulent) (septic) (staphylococcal) (streptococcal) (suppurative) (with periostitis) › vertebra”. Page updated September 29, 2026.
About coding vertebra osteomyelitis
The ICD-10-CM code for vertebra osteomyelitis is M46.20 (Osteomyelitis of vertebra, site unspecified). The official index lists 8 more specific codes, so check the documentation for details such as type, cause, site or severity before settling on M46.20.
Within M46.2, choose M46.20 (site unspecified) only when documentation doesn't support a more specific option: occipito-atlanto-axial region (M46.21), cervical region (M46.22), cervicothoracic region (M46.23), thoracic region (M46.24), thoracolumbar region (M46.25), lumbar region (M46.26), lumbosacral region (M46.27) and sacral and sacrococcygeal region (M46.28).
As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.
In MS-DRG v44.0, it is part of the grouping logic for DRG 456 (Spinal Fusion Except Cervical with Spinal Curvature, Malignancy, or Infection with MCC, relative weight 7.6244), DRG 457 (Spinal Fusion Except Cervical with Spinal Curvature, Malignancy, or Infection with CC, relative weight 5.3668), DRG 458 (Spinal Fusion Except Cervical with Spinal Curvature, Malignancy, or Infection without CC/MCC, relative weight 4.0388), DRG 539 (Osteomyelitis with MCC, relative weight 1.9385), DRG 540 (Osteomyelitis with CC, relative weight 1.3079) and DRG 541 (Osteomyelitis without CC/MCC, relative weight 0.8297), in MDC 08 (Diseases and Disorders of the Musculoskeletal System and Connective Tissue), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
More specific vertebra osteomyelitis codes (official index)
- cervical region M46.22 — Osteomyelitis of vertebra, cervical region
- cervicothoracic region M46.23 — Osteomyelitis of vertebra, cervicothoracic region
- lumbar region M46.26 — Osteomyelitis of vertebra, lumbar region
- lumbosacral region M46.27 — Osteomyelitis of vertebra, lumbosacral region
- occipito-atlanto-axial region M46.21 — Osteomyelitis of vertebra, occipito-atlanto-axial region
- sacrococcygeal region M46.28 — Osteomyelitis of vertebra, sacral and sacrococcygeal region
- thoracic region M46.24 — Osteomyelitis of vertebra, thoracic region
- thoracolumbar region M46.25 — Osteomyelitis of vertebra, thoracolumbar region
Common questions about vertebra osteomyelitis ICD-10 codes
What is the ICD-10 code for vertebra osteomyelitis?
- M46.20 — Osteomyelitis of vertebra, site unspecified. More specific codes apply when the documentation supports them: M46.22, M46.23, M46.26, M46.27 and others below.
What is the ICD-10 code for cervical region vertebra osteomyelitis?
- M46.22 — Osteomyelitis of vertebra, cervical region.
What is the ICD-10 code for cervicothoracic region vertebra osteomyelitis?
- M46.23 — Osteomyelitis of vertebra, cervicothoracic region.
What is the ICD-10 code for lumbar region vertebra osteomyelitis?
- M46.26 — Osteomyelitis of vertebra, lumbar region.
What is the ICD-10 code for lumbosacral region vertebra osteomyelitis?
- M46.27 — Osteomyelitis of vertebra, lumbosacral region.
What is the ICD-10 code for occipito-atlanto-axial region vertebra osteomyelitis?
- M46.21 — Osteomyelitis of vertebra, occipito-atlanto-axial region.
What is the ICD-10 code for sacrococcygeal region vertebra osteomyelitis?
- M46.28 — Osteomyelitis of vertebra, sacral and sacrococcygeal region.
Is M46.20 billable?
- Yes. M46.20 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can M46.20 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict M46.20 as a principal diagnosis.
Is M46.20 a CC or MCC?
- M46.20 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.