ICD-10-CM 2027
ICD-10 code for white matter disease
From the official ICD-10-CM alphabetic index entry “Disease, diseased › white matter”. Page updated September 29, 2026.
About coding white matter disease
The ICD-10-CM code for white matter disease is R90.82 (White matter disease, unspecified).
Within R90.8, choose R90.82 (White matter disease, unspecified) only when documentation doesn't support a more specific option: abnormal echoencephalogram (R90.81) and other abnormal findings on diagnostic imaging of central nervous system (R90.89).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 091 (Other Disorders of Nervous System with MCC, relative weight 1.7046), DRG 092 (Other Disorders of Nervous System with CC, relative weight 1.0239) and DRG 093 (Other Disorders of Nervous System without CC/MCC, relative weight 0.7783), in MDC 01 (Diseases and Disorders of the Nervous System), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
Common questions about white matter disease ICD-10 codes
What is the ICD-10 code for white matter disease?
- R90.82 — White matter disease, unspecified.
Is R90.82 billable?
- Yes. R90.82 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can R90.82 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict R90.82 as a principal diagnosis.
Is R90.82 a CC or MCC?
- No. R90.82 is neither a CC nor an MCC under MS-DRG v44.0.