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ICD-10-PCS 2027 procedure code

00503Z3Destruction of Brain using Laser Interstitial Thermal Therapy, Percutaneous Approach

✓ Valid for 2027O.R. procedure

Short description: Destruction of Brain using LITT, Perc Approach

Code last changed in FY2023 (effective October 1, 2022). Source: official FY2027 ICD-10-PCS release from CMS. Page updated September 29, 2026. About our data

About 00503Z3

00503Z3 is the ICD-10-PCS code for a destruction procedure on the brain using a percutaneous approach (qualifier: laser interstitial thermal therapy). In ICD-10-PCS, destruction means physical eradication of all or a portion of a body part by the direct use of energy, force, or a destructive agent.

For a different body part, codes include 005W3Z3 (cervical spinal cord), 005X3Z3 (thoracic spinal cord) and 005Y3Z3 (lumbar spinal cord).

The same procedure with a different approach is coded 00500Z3 (open) and 00504Z3 (percutaneous endoscopic).

It is an operating-room procedure in the MS-DRG logic for DRG 025 (Craniotomy and Endovascular Intracranial Procedures with MCC), DRG 026 (Craniotomy and Endovascular Intracranial Procedures with CC), DRG 027 (Craniotomy and Endovascular Intracranial Procedures without CC/MCC), DRG 820 (Lymphoma and Leukemia with Major O.R. Procedures with MCC), DRG 821 (Lymphoma and Leukemia with Major O.R. Procedures with CC) and DRG 822 (Lymphoma and Leukemia with Major O.R. Procedures without CC/MCC), under the surgical categories “Craniotomy and endovascular intracranial procedures”, “Lymphoma and Leukemia with Major O.R. Procedures”, “Myeloproliferative Disorders or Poorly Differentiated Neoplasms with Major O.R. Procedures” and 2 more.

It was added in FY2023, effective October 1, 2022.

What each character means

1. Section
0Medical and Surgical
2. Body System
0Central Nervous System and Cranial Nerves
3. Operation
5Destruction

Physical eradication of all or a portion of a body part by the direct use of energy, force, or a destructive agent

None of the body part is physically taken out

Includes: Fulguration of rectal polyp, cautery of skin lesion

4. Body Part
0Brain

Includes: Cerebrum; Corpus callosum; Encephalon

5. Approach
3Percutaneous

Entry, by puncture or minor incision, of instrumentation through the skin or mucous membrane and any other body layers necessary to reach the site of the procedure

6. Device
ZNo Device
7. Qualifier
3Laser Interstitial Thermal Therapy

Other versions of this procedure

MS-DRG v44.0 grouping

All DRGs →

Surgical MS-DRGs this procedure can group to, depending on the principal diagnosis's MDC.

MDC 24 · Multiple Significant Trauma · Craniotomy for Multiple Significant Trauma

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2023 (effective 10/1/2022): Added
  • No changes since FY2023.

Common questions about 00503Z3

Is 00503Z3 a valid ICD-10-PCS code for 2027?

Yes. 00503Z3 is valid for inpatient procedures from October 1, 2026 through September 30, 2027.

Is 00503Z3 an O.R. procedure?

Yes. 00503Z3 is an O.R. procedure in MS-DRG v44.0.

What DRG does 00503Z3 group to?

Depending on the principal diagnosis, 00503Z3 can group to MS-DRG 025, MS-DRG 026, MS-DRG 027, MS-DRG 820, MS-DRG 821 and MS-DRG 822.