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ICD-10-PCS 2027 procedure code

3E043GNIntroduction of Blood Brain Barrier Disruption Substance into Central Vein, Percutaneous Approach

✓ Valid for 2027

Short description: Introduce of BBBD Substance into Central Vein, Perc Approach

Code unchanged since ICD-10-PCS took effect on October 1, 2015. Source: official FY2027 ICD-10-PCS release from CMS. Page updated September 29, 2026. About our data

About 3E043GN

3E043GN is the ICD-10-PCS code for a introduction procedure on the central vein using a percutaneous approach with other therapeutic substance (qualifier: blood brain barrier disruption). In ICD-10-PCS, introduction means putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products.

In plain terms, this corresponds to disruption of blood brain barrier via infusion [BBBD], the ICD-9-CM procedure title it maps to (00.19).

For a different body part, codes include 3E033GN (peripheral vein), 3E053GN (peripheral artery) and 3E063GN (central artery).

The same procedure with a different approach is coded 3E040GN (open).

It doesn't appear in the MS-DRG procedure index, so on its own it doesn't change the DRG assignment.

It has been valid since ICD-10-PCS took effect on October 1, 2015.

What each character means

1. Section
3Administration
2. Body System
EPhysiological Systems and Anatomical Regions
3. Operation
0Introduction

Putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products

4. Body System / Region
4Central Vein
5. Approach
3Percutaneous

Entry, by puncture or minor incision, of instrumentation through the skin or mucous membrane and any other body layers necessary to reach the site of the procedure

6. Substance
GOther Therapeutic Substance

Includes: Anacaulase-bcdb; Bromelain-enriched Proteolytic Enzyme; Collagenase SANTYL Ointment; COSELA(tm) (Trilaciclib); ENSPRYNG(tm) (Satralizumab-mwge); Fostamatinib; Idarucizumab, Pradaxa(R)(dabigatran) reversal agent; NexoBrid(tm); Praxbind(R) (idarucizumab), Pradaxa(R)(dabigatran) reversal agent; SANTYL Ointment; Satralizumab-mwge; TAVALISSE(R); Trilaciclib

7. Qualifier
NBlood Brain Barrier Disruption

Other versions of this procedure

Different approach

ICD-9-CM equivalent

Converter →
  • 00.19Disruption of blood brain barrier via infusion [BBBD]approximate

From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about 3E043GN

Is 3E043GN a valid ICD-10-PCS code for 2027?

Yes. 3E043GN is valid for inpatient procedures from October 1, 2026 through September 30, 2027.

What is the ICD-9 procedure code for 3E043GN?

The CMS GEMs map 3E043GN to ICD-9-CM 00.19 (Disruption of blood brain barrier via infusion [BBBD]).