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ICD-10-PCS 2027 procedure code

3E0534ZIntroduction of Serum, Toxoid and Vaccine into Peripheral Artery, Percutaneous Approach

✓ Valid for 2027

Short description: Introduce Serum/Tox/Vaccine in Periph Art, Perc

Code unchanged since ICD-10-PCS took effect on October 1, 2015. Source: official FY2027 ICD-10-PCS release from CMS. Page updated September 29, 2026. About our data

About 3E0534Z

3E0534Z is the ICD-10-PCS code for a introduction procedure on the peripheral artery using a percutaneous approach with serum, toxoid and vaccine. In ICD-10-PCS, introduction means putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products.

In plain terms, this corresponds to injection of antidote, the ICD-9-CM procedure title it maps to (99.16).

For a different body part, codes include 3E0134Z (subcutaneous tissue), 3E0234Z (muscle), 3E0334Z (peripheral vein), 3E0434Z (central vein), 3E0634Z (central artery), 3E0934Z (nose) and 1 more.

The same procedure with a different approach is coded 3E0504Z (open).

With a different device, use 3E0533Z (anti-inflammatory), 3E0536Z (nutritional substance), 3E0537Z (electrolytic and water balance substance), 3E053FZ (intracirculatory anesthetic), 3E053HZ (radioactive substance), 3E053KZ (other diagnostic substance) and 5 more.

It doesn't appear in the MS-DRG procedure index, so on its own it doesn't change the DRG assignment.

It has been valid since ICD-10-PCS took effect on October 1, 2015.

What each character means

1. Section
3Administration
2. Body System
EPhysiological Systems and Anatomical Regions
3. Operation
0Introduction

Putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products

4. Body System / Region
5Peripheral Artery
5. Approach
3Percutaneous

Entry, by puncture or minor incision, of instrumentation through the skin or mucous membrane and any other body layers necessary to reach the site of the procedure

6. Substance
4Serum, Toxoid and Vaccine
7. Qualifier
ZNo Qualifier

Other versions of this procedure

Different approach

ICD-9-CM equivalent

Converter →
  • 99.16Injection of antidoteapproximate

From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about 3E0534Z

Is 3E0534Z a valid ICD-10-PCS code for 2027?

Yes. 3E0534Z is valid for inpatient procedures from October 1, 2026 through September 30, 2027.

What is the ICD-9 procedure code for 3E0534Z?

The CMS GEMs map 3E0534Z to ICD-9-CM 99.16 (Injection of antidote).