ICD-10-PCS 2027 procedure code

3E06305Introduction of Other Antineoplastic into Central Artery, Percutaneous Approach

✓ Valid for 2027

Short description: Introduce Oth Antineoplastic in Central Art, Perc

Code unchanged since ICD-10-PCS took effect on October 1, 2015. Source: official FY2027 ICD-10-PCS release from CMS. Page updated September 29, 2026. About our data

About 3E06305

3E06305 is the ICD-10-PCS code for a introduction procedure on the central artery using a percutaneous approach with antineoplastic (qualifier: other antineoplastic). In ICD-10-PCS, introduction means putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products.

In plain terms, this corresponds to total body perfusion and injection or infusion of cancer chemotherapeutic substance, the ICD-9-CM procedure titles it maps to (39.96 and 99.25).

For a different body part, codes include 3E01305 (subcutaneous tissue), 3E02305 (muscle), 3E03305 (peripheral vein), 3E04305 (central vein), 3E05305 (peripheral artery), 3E09305 (nose) and 21 more.

The same procedure with a different approach is coded 3E06005 (open).

It doesn't appear in the MS-DRG procedure index, so on its own it doesn't change the DRG assignment.

It has been valid since ICD-10-PCS took effect on October 1, 2015.

What each character means

1. Section: 3Administration
2. Body System: EPhysiological Systems and Anatomical Regions
3. Operation: 0Introduction
Putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products
4. Body System / Region: 6Central Artery
5. Approach: 3Percutaneous
Entry, by puncture or minor incision, of instrumentation through the skin or mucous membrane and any other body layers necessary to reach the site of the procedure
6. Substance: 0Antineoplastic
Includes: Amivantamab Monoclonal Antibody; Lurbinectedin; RYBREVANT (tm) (Amivantamab Monoclonal Antibody); ZEPZELCA(tm) (Lurbinectedin)
7. Qualifier: 5Other Antineoplastic

Other versions of this procedure

Different body system / region

Different approach

3E06005Open

Different qualifier

ICD-9-CM equivalent

Converter →

39.96Total body perfusionapproximate
99.25Injection or infusion of cancer chemotherapeutic substanceapproximate

From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.

Code history

2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
2026
2027

FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
No changes since FY2016.

Common questions about 3E06305

Is 3E06305 a valid ICD-10-PCS code for 2027?: Yes. 3E06305 is valid for inpatient procedures from October 1, 2026 through September 30, 2027.
What is the ICD-9 procedure code for 3E06305?: The CMS GEMs map 3E06305 to ICD-9-CM 39.96 (Total body perfusion) and 99.25 (Injection or infusion of cancer chemotherapeutic substance).