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ICD-10-PCS 2027 procedure code

3E0D705Introduction of Other Antineoplastic into Mouth and Pharynx, Via Natural or Artificial Opening

✓ Valid for 2027

Short description: Introduce of Oth Antineoplastic into Mouth/Phar, Via Opening

Code unchanged since ICD-10-PCS took effect on October 1, 2015. Source: official FY2027 ICD-10-PCS release from CMS. Page updated September 29, 2026. About our data

About 3E0D705

3E0D705 is the ICD-10-PCS code for a introduction procedure on the mouth and pharynx using a via natural or artificial opening approach with antineoplastic (qualifier: other antineoplastic). In ICD-10-PCS, introduction means putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products.

In plain terms, this corresponds to injection or infusion of cancer chemotherapeutic substance, the ICD-9-CM procedure title it maps to (99.25).

For a different body part, codes include 3E09705 (nose), 3E0B705 (ear), 3E0C705 (eye), 3E0E705 (products of conception), 3E0F705 (respiratory tract), 3E0G705 (upper GI) and 9 more.

The same procedure with a different approach is coded 3E0D305 (percutaneous) and 3E0DX05 (external).

It doesn't appear in the MS-DRG procedure index, so on its own it doesn't change the DRG assignment.

It has been valid since ICD-10-PCS took effect on October 1, 2015.

What each character means

1. Section
3Administration
2. Body System
EPhysiological Systems and Anatomical Regions
3. Operation
0Introduction

Putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products

4. Body System / Region
DMouth and Pharynx
5. Approach
7Via Natural or Artificial Opening

Entry of instrumentation through a natural or artificial external opening to reach the site of the procedure

6. Substance
0Antineoplastic

Includes: Amivantamab Monoclonal Antibody; Lurbinectedin; RYBREVANT (tm) (Amivantamab Monoclonal Antibody); ZEPZELCA(tm) (Lurbinectedin)

7. Qualifier
5Other Antineoplastic

Other versions of this procedure

ICD-9-CM equivalent

Converter →
  • 99.25Injection or infusion of cancer chemotherapeutic substanceapproximate

From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about 3E0D705

Is 3E0D705 a valid ICD-10-PCS code for 2027?

Yes. 3E0D705 is valid for inpatient procedures from October 1, 2026 through September 30, 2027.

What is the ICD-9 procedure code for 3E0D705?

The CMS GEMs map 3E0D705 to ICD-9-CM 99.25 (Injection or infusion of cancer chemotherapeutic substance).