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ICD-10-PCS 2027 procedure code

3E0K8GCIntroduction of Other Therapeutic Substance into Genitourinary Tract, Via Natural or Artificial Opening Endoscopic

✓ Valid for 2027

Short description: Introduction of Oth Therap Subst into GU Tract, Endo

Code unchanged since ICD-10-PCS took effect on October 1, 2015. Source: official FY2027 ICD-10-PCS release from CMS. Page updated September 29, 2026. About our data

About 3E0K8GC

3E0K8GC is the ICD-10-PCS code for a introduction procedure on the genitourinary tract using a via natural or artificial opening endoscopic approach with other therapeutic substance (qualifier: other substance). In ICD-10-PCS, introduction means putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products.

In plain terms, this corresponds to injection or infusion of other therapeutic or prophylactic substance, the ICD-9-CM procedure title it maps to (99.29).

For a different body part, codes include 3E0E8GC (products of conception), 3E0F8GC (respiratory tract), 3E0G8GC (upper GI), 3E0H8GC (lower GI), 3E0J8GC (biliary and pancreatic tract), 3E0N8GC (male reproductive) and 1 more.

The same procedure with a different approach is coded 3E0K3GC (percutaneous), 3E0K4GC (percutaneous endoscopic) and 3E0K7GC (via natural or artificial opening).

It doesn't appear in the MS-DRG procedure index, so on its own it doesn't change the DRG assignment.

It has been valid since ICD-10-PCS took effect on October 1, 2015.

What each character means

1. Section
3Administration
2. Body System
EPhysiological Systems and Anatomical Regions
3. Operation
0Introduction

Putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products

4. Body System / Region
KGenitourinary Tract
5. Approach
8Via Natural or Artificial Opening Endoscopic

Entry of instrumentation through a natural or artificial external opening to reach and visualize the site of the procedure

6. Substance
GOther Therapeutic Substance

Includes: Anacaulase-bcdb; Bromelain-enriched Proteolytic Enzyme; Collagenase SANTYL Ointment; COSELA(tm) (Trilaciclib); ENSPRYNG(tm) (Satralizumab-mwge); Fostamatinib; Idarucizumab, Pradaxa(R)(dabigatran) reversal agent; NexoBrid(tm); Praxbind(R) (idarucizumab), Pradaxa(R)(dabigatran) reversal agent; SANTYL Ointment; Satralizumab-mwge; TAVALISSE(R); Trilaciclib

7. Qualifier
COther Substance

Other versions of this procedure

ICD-9-CM equivalent

Converter →
  • 99.29Injection or infusion of other therapeutic or prophylactic substanceapproximate

From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about 3E0K8GC

Is 3E0K8GC a valid ICD-10-PCS code for 2027?

Yes. 3E0K8GC is valid for inpatient procedures from October 1, 2026 through September 30, 2027.

What is the ICD-9 procedure code for 3E0K8GC?

The CMS GEMs map 3E0K8GC to ICD-9-CM 99.29 (Injection or infusion of other therapeutic or prophylactic substance).