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ICD-10-PCS 2027 procedure code

3E0X3GCIntroduction of Other Therapeutic Substance into Cranial Nerves, Percutaneous Approach

✓ Valid for 2027

Short description: Introduce Oth Therap Subst in Cranial Nrv, Perc

Code unchanged since ICD-10-PCS took effect on October 1, 2015. Source: official FY2027 ICD-10-PCS release from CMS. Page updated September 29, 2026. About our data

About 3E0X3GC

3E0X3GC is the ICD-10-PCS code for a introduction procedure on the cranial nerves using a percutaneous approach with other therapeutic substance (qualifier: other substance). In ICD-10-PCS, introduction means putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products.

In plain terms, this corresponds to injection of other agent, except neurolytic, the ICD-9-CM procedure title it maps to (04.89).

For a different body part, codes include 3E013GC (subcutaneous tissue), 3E023GC (muscle), 3E033GC (peripheral vein), 3E043GC (central vein), 3E053GC (peripheral artery), 3E063GC (central artery) and 25 more.

It doesn't appear in the MS-DRG procedure index, so on its own it doesn't change the DRG assignment.

It has been valid since ICD-10-PCS took effect on October 1, 2015.

What each character means

1. Section
3Administration
2. Body System
EPhysiological Systems and Anatomical Regions
3. Operation
0Introduction

Putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products

4. Body System / Region
XCranial Nerves
5. Approach
3Percutaneous

Entry, by puncture or minor incision, of instrumentation through the skin or mucous membrane and any other body layers necessary to reach the site of the procedure

6. Substance
GOther Therapeutic Substance

Includes: Anacaulase-bcdb; Bromelain-enriched Proteolytic Enzyme; Collagenase SANTYL Ointment; COSELA(tm) (Trilaciclib); ENSPRYNG(tm) (Satralizumab-mwge); Fostamatinib; Idarucizumab, Pradaxa(R)(dabigatran) reversal agent; NexoBrid(tm); Praxbind(R) (idarucizumab), Pradaxa(R)(dabigatran) reversal agent; SANTYL Ointment; Satralizumab-mwge; TAVALISSE(R); Trilaciclib

7. Qualifier
COther Substance

Other versions of this procedure

ICD-9-CM equivalent

Converter →
  • 04.89Injection of other agent, except neurolyticapproximate

From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about 3E0X3GC

Is 3E0X3GC a valid ICD-10-PCS code for 2027?

Yes. 3E0X3GC is valid for inpatient procedures from October 1, 2026 through September 30, 2027.

What is the ICD-9 procedure code for 3E0X3GC?

The CMS GEMs map 3E0X3GC to ICD-9-CM 04.89 (Injection of other agent, except neurolytic).