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ICD-10-PCS 2027 procedure code

XHR4XGAReplacement of Right Upper Extremity Skin with Prademagene Zamikeracel, Genetically Engineered Autologous Cell Therapy, External Approach, New Technology Group 10

✓ Valid for 2027O.R. procedure

Short description: Replace RUE Skin w pz-cel, Extern, New Tech 10

Code last changed in FY2025 (effective October 1, 2024). Source: official FY2027 ICD-10-PCS release from CMS. Page updated September 29, 2026. About our data

About XHR4XGA

XHR4XGA is the ICD-10-PCS code for a replacement procedure on the skin, right upper extremity using an external approach with prademagene zamikeracel, genetically engineered autologous cell therapy (qualifier: new technology group 10). In ICD-10-PCS, replacement means putting in or on biological or synthetic material that physically takes the place and/or function of all or a portion of a body part.

For a different body part, codes include XHR0XGA (skin, head and neck), XHR1XGA (skin, chest), XHR2XGA (skin, abdomen), XHR3XGA (skin, back), XHR5XGA (skin, left upper extremity), XHR6XGA (skin, right lower extremity) and 1 more.

It is an operating-room procedure in the MS-DRG logic for DRG 018 (Chimeric Antigen Receptor (CAR) T-Cell and Other Immunotherapies), under the surgical category “Chimeric Antigen Receptor (CAR) T-Cell and Other Immunotherapies”.

It was added in FY2025, effective October 1, 2024.

What each character means

1. Section
XNew Technology
2. Body System
HSkin, Subcutaneous Tissue, Fascia and Breast
3. Operation
RReplacement

Putting in or on biological or synthetic material that physically takes the place and/or function of all or a portion of a body part

4. Body Part
4Skin, Right Upper Extremity
5. Approach
XExternal

Procedures performed directly on the skin or mucous membrane and procedures performed indirectly by the application of external force through the skin or mucous membrane

6. Device / Substance / Technology
GPrademagene Zamikeracel, Genetically Engineered Autologous Cell Therapy
7. Qualifier
ANew Technology Group 10

Other versions of this procedure

MS-DRG v44.0 grouping

All DRGs →

Surgical MS-DRGs this procedure can group to, depending on the principal diagnosis's MDC.

MDC PRE · Pre-MDC · Chimeric Antigen Receptor (CAR) T-Cell and Other Immunotherapies

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2025 (effective 10/1/2024): Added
  • No changes since FY2025.

Common questions about XHR4XGA

Is XHR4XGA a valid ICD-10-PCS code for 2027?

Yes. XHR4XGA is valid for inpatient procedures from October 1, 2026 through September 30, 2027.

Is XHR4XGA an O.R. procedure?

Yes. XHR4XGA is an O.R. procedure in MS-DRG v44.0.

What DRG does XHR4XGA group to?

Depending on the principal diagnosis, XHR4XGA can group to MS-DRG 018.