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ICD-10-PCS 2027 procedure code

XW0337CIntroduction of Zimislecel Allogeneic Stem Cell-Derived Islet Cell Therapy into Peripheral Vein, Percutaneous Approach, New Technology Group 12

✓ Valid for 2027New for 2027Non-O.R. procedure

Short description: Introduce Zimislecel in Periph Vein, Perc, New Tech 12

Code last changed in FY2027 (effective October 1, 2026). Source: official FY2027 ICD-10-PCS release from CMS. Page updated September 29, 2026. About our data

About XW0337C

XW0337C is the ICD-10-PCS code for a introduction procedure on the peripheral vein using a percutaneous approach with zimislecel allogeneic stem cell-derived islet cell therapy (qualifier: new technology group 12). In ICD-10-PCS, introduction means putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products.

With a different device, use XW0336C (landiolol antiarrhythmic).

It is a non-O.R. procedure that is part of the MS-DRG logic for DRG 008 (Simultaneous Pancreas, Islet Cell and Kidney Transplant), DRG 010 (Pancreas or Islet Cell Transplant) and DRG 019 (Simultaneous Pancreas, Islet Cell and Kidney Transplant with Hemodialysis), under the surgical categories “Simultaneous Pancreas, Islet Cell and Kidney Transplant”, “Pancreas or Islet Cell Transplant” and “Simultaneous Pancreas, Islet Cell and Kidney Transplant with Hemodialysis”.

It was added in FY2027, effective October 1, 2026.

What each character means

1. Section
XNew Technology
2. Body System
WAnatomical Regions
3. Operation
0Introduction

Putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products

4. Body Part
3Peripheral Vein
5. Approach
3Percutaneous

Entry, by puncture or minor incision, of instrumentation through the skin or mucous membrane and any other body layers necessary to reach the site of the procedure

6. Device / Substance / Technology
7Zimislecel Allogeneic Stem Cell-Derived Islet Cell Therapy
7. Qualifier
CNew Technology Group 12

Other versions of this procedure

Different device / substance / technology

MS-DRG v44.0 grouping

All DRGs →

Surgical MS-DRGs this procedure can group to, depending on the principal diagnosis's MDC.

MDC PRE · Pre-MDC · Simultaneous Pancreas, Islet Cell and Kidney Transplant

MDC PRE · Pre-MDC · Pancreas or Islet Cell Transplant

MDC PRE · Pre-MDC · Simultaneous Pancreas, Islet Cell and Kidney Transplant with Hemodialysis

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2027 (effective 10/1/2026): Added

Common questions about XW0337C

Is XW0337C a valid ICD-10-PCS code for 2027?

Yes. XW0337C is valid for inpatient procedures from October 1, 2026 through September 30, 2027.

Is XW0337C an O.R. procedure?

No. XW0337C is designated non-O.R. in MS-DRG v44.0.

What DRG does XW0337C group to?

Depending on the principal diagnosis, XW0337C can group to MS-DRG 008, MS-DRG 010 and MS-DRG 019.