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ICD-10-PCS 2027 procedure code

XW04372Introduction of Inactivated Coagulation Factor Xa into Central Vein, Percutaneous Approach, New Technology Group 2

✓ Valid for 2027

Short description: Introduce Coag Factor Xa in Central Vein, Perc, New Tech 2

Code last changed in FY2020 (effective October 1, 2019). Source: official FY2027 ICD-10-PCS release from CMS. Page updated September 29, 2026. About our data

About XW04372

XW04372 is the ICD-10-PCS code for a introduction procedure on the central vein using a percutaneous approach with coagulation factor xa, inactivated (qualifier: new technology group 2). In ICD-10-PCS, introduction means putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products.

In plain terms, this corresponds to injection or infusion of other therapeutic or prophylactic substance, the ICD-9-CM procedure title it maps to (99.29).

For a different body part, codes include XW03372 (peripheral vein).

It doesn't appear in the MS-DRG procedure index, so on its own it doesn't change the DRG assignment.

It was added in FY2017, effective October 1, 2016.

What each character means

1. Section
XNew Technology
2. Body System
WAnatomical Regions
3. Operation
0Introduction

Putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products

4. Body Part
4Central Vein
5. Approach
3Percutaneous

Entry, by puncture or minor incision, of instrumentation through the skin or mucous membrane and any other body layers necessary to reach the site of the procedure

6. Device / Substance / Technology
7Coagulation Factor Xa, Inactivated

Includes: Andexanet Alfa, Factor Xa Inhibitor Reversal Agent; Andexxa; Coagulation Factor Xa, (Recombinant) Inactivated; Factor Xa Inhibitor Reversal Agent, Andexanet Alfa

7. Qualifier
2New Technology Group 2

Other versions of this procedure

Different body part

ICD-9-CM equivalent

Converter →
  • 99.29Injection or infusion of other therapeutic or prophylactic substanceapproximate

From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2017 (effective 10/1/2016): Added
  • FY2020 (effective 10/1/2019): Title revised — was “Introduction of Andexanet Alfa, Factor Xa Inhibitor Reversal Agent into Central Vein, Percutaneous Approach, New Technology Group 2”

Common questions about XW04372

Is XW04372 a valid ICD-10-PCS code for 2027?

Yes. XW04372 is valid for inpatient procedures from October 1, 2026 through September 30, 2027.

What is the ICD-9 procedure code for XW04372?

The CMS GEMs map XW04372 to ICD-9-CM 99.29 (Injection or infusion of other therapeutic or prophylactic substance).