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ICD-10-PCS 2027 procedure code

XW043B3Introduction of Cytarabine and Daunorubicin Liposome Antineoplastic into Central Vein, Percutaneous Approach, New Technology Group 3

✓ Valid for 2027

Short description: Introduce cytarab/daunorub in Central Vein, Perc, New Tech 3

Code last changed in FY2018 (effective October 1, 2017). Source: official FY2027 ICD-10-PCS release from CMS. Page updated September 29, 2026. About our data

About XW043B3

XW043B3 is the ICD-10-PCS code for a introduction procedure on the central vein using a percutaneous approach with cytarabine and daunorubicin liposome antineoplastic (qualifier: new technology group 3). In ICD-10-PCS, introduction means putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products.

In plain terms, this corresponds to injection or infusion of cancer chemotherapeutic substance, the ICD-9-CM procedure title it maps to (99.25).

For a different body part, codes include XW033B3 (peripheral vein).

With a different device, use XW043F3 (other new technology therapeutic substance).

It doesn't appear in the MS-DRG procedure index, so on its own it doesn't change the DRG assignment.

It was added in FY2018, effective October 1, 2017.

What each character means

1. Section
XNew Technology
2. Body System
WAnatomical Regions
3. Operation
0Introduction

Putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products

4. Body Part
4Central Vein
5. Approach
3Percutaneous

Entry, by puncture or minor incision, of instrumentation through the skin or mucous membrane and any other body layers necessary to reach the site of the procedure

6. Device / Substance / Technology
BCytarabine and Daunorubicin Liposome Antineoplastic

Includes: VYXEOS(tm)

7. Qualifier
3New Technology Group 3

Other versions of this procedure

Different body part

Different device / substance / technology

ICD-9-CM equivalent

Converter →
  • 99.25Injection or infusion of cancer chemotherapeutic substanceapproximate

From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2018 (effective 10/1/2017): Added
  • No changes since FY2018.

Common questions about XW043B3

Is XW043B3 a valid ICD-10-PCS code for 2027?

Yes. XW043B3 is valid for inpatient procedures from October 1, 2026 through September 30, 2027.

What is the ICD-9 procedure code for XW043B3?

The CMS GEMs map XW043B3 to ICD-9-CM 99.25 (Injection or infusion of cancer chemotherapeutic substance).