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ICD-10-PCS 2027 procedure code

XW043CAIntroduction of Zanidatamab Antineoplastic into Central Vein, Percutaneous Approach, New Technology Group 10

✓ Valid for 2027

Short description: Introduce Zanidatamab in Central Vein, Perc, New Tech 10

Code last changed in FY2025 (effective October 1, 2024). Source: official FY2027 ICD-10-PCS release from CMS. Page updated September 29, 2026. About our data

About XW043CA

XW043CA is the ICD-10-PCS code for a introduction procedure on the central vein using a percutaneous approach with zanidatamab antineoplastic (qualifier: new technology group 10). In ICD-10-PCS, introduction means putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products.

For a different body part, codes include XW033CA (peripheral vein).

With a different device, use XW0433A (maribavir anti-infective), XW0434A (stem cells, somatic), XW0435A (ifezuntirgene inilparvovec), XW0438A (mineral-based topical hemostatic agent), XW0439A (odronextamab antineoplastic), XW043BA (vancomycin-eluting bone void filler) and 3 more.

It doesn't appear in the MS-DRG procedure index, so on its own it doesn't change the DRG assignment.

It was added in FY2025, effective October 1, 2024.

What each character means

1. Section
XNew Technology
2. Body System
WAnatomical Regions
3. Operation
0Introduction

Putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products

4. Body Part
4Central Vein
5. Approach
3Percutaneous

Entry, by puncture or minor incision, of instrumentation through the skin or mucous membrane and any other body layers necessary to reach the site of the procedure

6. Device / Substance / Technology
CZanidatamab Antineoplastic

Includes: ZIIHERA(R)

7. Qualifier
ANew Technology Group 10

Other versions of this procedure

Different body part

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2025 (effective 10/1/2024): Added
  • No changes since FY2025.

Common questions about XW043CA

Is XW043CA a valid ICD-10-PCS code for 2027?

Yes. XW043CA is valid for inpatient procedures from October 1, 2026 through September 30, 2027.