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ICD-10-PCS 2027 procedure code

XW0DXVBIntroduction of Xanomeline and Trospium Chloride into Mouth and Pharynx, External Approach, New Technology Group 11

✓ Valid for 2027

Short description: Introduce Xanomln w Trosp in Mouth/Phar, Extern, New Tech 11

Code last changed in FY2026 (effective October 1, 2025). Source: official FY2027 ICD-10-PCS release from CMS. Page updated September 29, 2026. About our data

About XW0DXVB

XW0DXVB is the ICD-10-PCS code for a introduction procedure on the mouth and pharynx using an external approach with xanomeline and trospium chloride (qualifier: new technology group 11). In ICD-10-PCS, introduction means putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products.

It doesn't appear in the MS-DRG procedure index, so on its own it doesn't change the DRG assignment.

It was added in FY2026, effective October 1, 2025.

What each character means

1. Section
XNew Technology
2. Body System
WAnatomical Regions
3. Operation
0Introduction

Putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products

4. Body Part
DMouth and Pharynx
5. Approach
XExternal

Procedures performed directly on the skin or mucous membrane and procedures performed indirectly by the application of external force through the skin or mucous membrane

6. Device / Substance / Technology
VXanomeline and Trospium Chloride

Includes: COBENFY(tm)

7. Qualifier
BNew Technology Group 11

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2026 (effective 10/1/2025): Added
  • No changes since FY2026.

Common questions about XW0DXVB

Is XW0DXVB a valid ICD-10-PCS code for 2027?

Yes. XW0DXVB is valid for inpatient procedures from October 1, 2026 through September 30, 2027.