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ICD-10-PCS 2027 procedure code

XXE5XBBMeasurement of Infection and Immune Response, Gene Expression Testing System, New Technology Group 11

✓ Valid for 2027

Short description: Measure of Infect/Imm Respons, Gene Exprsion, New Tech 11

Code last changed in FY2026 (effective October 1, 2025). Source: official FY2027 ICD-10-PCS release from CMS. Page updated September 29, 2026. About our data

About XXE5XBB

XXE5XBB is the ICD-10-PCS code for a measurement procedure on the circulatory using an external approach with infection and immune response, gene expression testing system (qualifier: new technology group 11). In ICD-10-PCS, measurement means determining the level of a physiological or physical function at a point in time.

It doesn't appear in the MS-DRG procedure index, so on its own it doesn't change the DRG assignment.

It was added in FY2026, effective October 1, 2025.

What each character means

1. Section
XNew Technology
2. Body System
XPhysiological Systems
3. Operation
EMeasurement

Determining the level of a physiological or physical function at a point in time

4. Body Part
5Circulatory
5. Approach
XExternal

Procedures performed directly on the skin or mucous membrane and procedures performed indirectly by the application of external force through the skin or mucous membrane

6. Device / Substance / Technology
BInfection and Immune Response, Gene Expression Testing System
7. Qualifier
BNew Technology Group 11

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2026 (effective 10/1/2025): Added
  • No changes since FY2026.

Common questions about XXE5XBB

Is XXE5XBB a valid ICD-10-PCS code for 2027?

Yes. XXE5XBB is valid for inpatient procedures from October 1, 2026 through September 30, 2027.