ICD-9-CM diagnosis code (retired)
288.4 — Hemophagocytic syndromes
ICD-9-CM was replaced by ICD-10 on October 1, 2015. These are the ICD-10-CM equivalents from the CMS General Equivalence Mappings.
About ICD-9-CM 288.4
288.4 is an ICD-9-CM diagnosis code for Hemophagocytic syndromes. ICD-9-CM was retired for U.S. claims on October 1, 2015, when ICD-10-CM took over.
The CMS General Equivalence Mappings translate it to 3 ICD-10-CM codes, such as D76.1 (Hemophagocytic lymphohistiocytosis), D76.2 (Hemophagocytic syndrome, infection-associated) and D76.3 (Other histiocytosis syndromes). All of these are approximate matches, so review the record to pick the right one.
ICD-10-CM equivalents
Common questions about 288.4
GEMs are a translation aid, not a substitute for coding from the record. The 2027 ICD-10 code set has changed since the last GEMs release in 2018. Page updated September 29, 2026.