ICD-9-CM diagnosis code (retired)
644.21 — Early onset of delivery, delivered, with or without mention of antepartum condition
About ICD-9-CM 644.21
644.21 is an ICD-9-CM diagnosis code for early onset of delivery, delivered, with or without mention of antepartum condition. ICD-9-CM was retired for U.S. claims on October 1, 2015, when ICD-10-CM took over.
The CMS General Equivalence Mappings translate it to 3 ICD-10-CM codes, such as O60.12X0 (Preterm labor second trimester with preterm delivery second trimester, not applicable or unspecified), O60.13X0 (Preterm labor second trimester with preterm delivery third trimester, not applicable or unspecified) and O60.14X0 (Preterm labor third trimester with preterm delivery third trimester, not applicable or unspecified). All of these are approximate matches, so review the record to pick the right one.
ICD-10-CM equivalents
- O60.12X0Preterm labor second trimester with preterm delivery second trimester, not applicable or unspecifiedapproximate
- O60.13X0Preterm labor second trimester with preterm delivery third trimester, not applicable or unspecifiedapproximate
- O60.14X0Preterm labor third trimester with preterm delivery third trimester, not applicable or unspecifiedapproximate
Common questions about 644.21
GEMs are a translation aid, not a substitute for coding from the record. The 2027 ICD-10 code set has changed since the last GEMs release in 2018. Page updated September 29, 2026.