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ICD-9-CM diagnosis code (retired)

646.21 — Unspecified renal disease in pregnancy, without mention of hypertension, delivered, with or without mention of antepartum condition

ICD-9-CM was replaced by ICD-10 on October 1, 2015. These are the ICD-10-CM equivalents from the CMS General Equivalence Mappings.

About ICD-9-CM 646.21

646.21 is an ICD-9-CM diagnosis code for unspecified renal disease in pregnancy, without mention of hypertension, delivered, with or without mention of antepartum condition. ICD-9-CM was retired for U.S. claims on October 1, 2015, when ICD-10-CM took over.

The CMS General Equivalence Mappings translate it to 4 ICD-10-CM codes, such as O12.14 (Gestational proteinuria, complicating childbirth), O26.831 (Pregnancy related renal disease, first trimester) and O26.832 (Pregnancy related renal disease, second trimester). All of these are approximate matches, so review the record to pick the right one.

ICD-10-CM equivalents

Common questions about 646.21

What is the ICD-10 code for ICD-9 646.21?

The GEMs map 646.21 to ICD-10-CM O12.14, O26.831, O26.832 and O26.833.

GEMs are a translation aid, not a substitute for coding from the record. The 2027 ICD-10 code set has changed since the last GEMs release in 2018. Page updated September 29, 2026.