ICD-9-CM diagnosis code (retired)
648.21 — Anemia of mother, delivered, with or without mention of antepartum condition
About ICD-9-CM 648.21
648.21 is an ICD-9-CM diagnosis code for anemia of mother, delivered, with or without mention of antepartum condition. ICD-9-CM was retired for U.S. claims on October 1, 2015, when ICD-10-CM took over.
The CMS General Equivalence Mappings translate it to 4 ICD-10-CM codes, such as O99.011 (Anemia complicating pregnancy, first trimester), O99.012 (Anemia complicating pregnancy, second trimester) and O99.013 (Anemia complicating pregnancy, third trimester). All of these are approximate matches, so review the record to pick the right one.
ICD-10-CM equivalents
Common questions about 648.21
GEMs are a translation aid, not a substitute for coding from the record. The 2027 ICD-10 code set has changed since the last GEMs release in 2018. Page updated September 29, 2026.