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ICD-9-CM diagnosis code (retired)

999.49 — Anaphylactic reaction due to other serum

ICD-9-CM was replaced by ICD-10 on October 1, 2015. These are the ICD-10-CM equivalents from the CMS General Equivalence Mappings.

About ICD-9-CM 999.49

999.49 is an ICD-9-CM diagnosis code for anaphylactic reaction due to other serum. ICD-9-CM was retired for U.S. claims on October 1, 2015, when ICD-10-CM took over.

The CMS General Equivalence Mappings translate it to one ICD-10-CM code, T80.59XA (Anaphylactic reaction due to other serum, initial encounter). The match is approximate, so confirm it against the record.

ICD-10-CM equivalents

Common questions about 999.49

What is the ICD-10 code for ICD-9 999.49?

The GEMs map 999.49 to ICD-10-CM T80.59XA.

GEMs are a translation aid, not a substitute for coding from the record. The 2027 ICD-10 code set has changed since the last GEMs release in 2018. Page updated September 29, 2026.