C5278Application of low cost skin substitute graft to face, scalp, eyelids, mouth, neck, ears, orbits, genitalia, hands, feet, and/or multiple digits, total wound surface area greater than or equal to 100 sq cm; each additional 100 sq cm wound surface area, or part thereof, or each additional 1% of body area of infants and children, or part thereof (list separately in addition to code for primary procedure)

C5278 is an HCPCS Level II code in the C series (outpatient PPS (temporary codes)), describing application of low cost skin substitute graft to face, scalp, eyelids, mouth, neck, ears, orbits, genitalia, hands, feet, and/or multiple digits, total wound surface area greater than or equal to 100 sq cm; each additional 100 sq cm wound surface area, or part thereof, or each additional 1% of body area of infants and children, or part thereof (list separately in addition to code for primary procedure).

It was added to HCPCS effective 01/01/2014, and its current record took effect 01/01/2026.

It was terminated on 12/31/2025 and can't be billed for later dates of service.

Its Medicare coverage code is "D", meaning special Medicare coverage instructions apply.