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ICD-10-CM 2027 diagnosis code

C52Malignant neoplasm of vagina

✓ Billable / specificFemale only

C52 is a valid, billable ICD-10-CM code for malignant neoplasm of vagina. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About C52

C52 is the ICD-10-CM diagnosis code for malignant neoplasm of vagina. It belongs to block C51-C58 (malignant neoplasms of female genital organs) and chapter 2 (neoplasms). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Don't report C52 together with the conditions in its Excludes1 note: carcinoma in situ of vagina (D07.2).

It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.

In MS-DRG v44.0, it is part of the grouping logic for DRG 731 (Uterine and Adnexa Procedures for Malignancy with MCC, relative weight 3.5478), DRG 732 (Uterine and Adnexa Procedures for Malignancy with CC, relative weight 1.9208), DRG 733 (Uterine and Adnexa Procedures for Malignancy without CC/MCC, relative weight 1.4324), DRG 754 (Malignancy, Female Reproductive System with MCC, relative weight 1.8092), DRG 755 (Malignancy, Female Reproductive System with CC, relative weight 1.149) and DRG 756 (Malignancy, Female Reproductive System without CC/MCC, relative weight 0.8645), in MDC 13 (Diseases and Disorders of the Female Reproductive System), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It is on the CMS list of diagnoses consistent only with female patients (the sex-conflict edit itself was retired in FY2025).

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Before ICD-10, this condition was coded in ICD-9-CM as 184.0 (malignant neoplasm of vagina).

Coding notes

Excludes1Not coded here — never report together with this code
  • carcinoma in situ of vagina (D07.2)

Notes that apply from higher levels

Instructions written at a parent level also apply to C52.

Broader instructions also apply from C51-C58 Malignant neoplasms of female genital organs and Chapter 2: Neoplasms.

Table of Drugs & Neoplasms entries

Codes whose notes reference C52

MS-DRG v44.0 grouping

All DRGs →

Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.

ICD-9-CM equivalent

Converter →
  • 184.0Malignant neoplasm of vaginaexact

From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about C52

Is C52 billable?

Yes. C52 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can C52 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict C52 as a principal diagnosis.

Is C52 a CC or MCC?

No. C52 is neither a CC nor an MCC under MS-DRG v44.0.

What DRG does C52 group to?

C52 is used in the MS-DRG v44.0 logic for MS-DRG 731 (Uterine and Adnexa Procedures for Malignancy with MCC), MS-DRG 732 (Uterine and Adnexa Procedures for Malignancy with CC), MS-DRG 733 (Uterine and Adnexa Procedures for Malignancy without CC/MCC), MS-DRG 754 (Malignancy, Female Reproductive System with MCC), MS-DRG 755 (Malignancy, Female Reproductive System with CC) and MS-DRG 756 (Malignancy, Female Reproductive System without CC/MCC). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.

What is the ICD-9 code for C52?

The CMS General Equivalence Mappings map C52 to ICD-9-CM 184.0.