A52.00Cardiovascular syphilis, unspecified

A52.00 is the ICD-10-CM diagnosis code for cardiovascular syphilis, unspecified. It belongs to category A52 (late syphilis), block A50-A64 (infections with a predominantly sexual mode of transmission) and chapter 1 (certain infectious and parasitic diseases). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within A52.0, choose A52.00 (Cardiovascular syphilis, unspecified) only when documentation doesn't support a more specific option: syphilitic aneurysm of aorta (A52.01), syphilitic aortitis (A52.02), syphilitic endocarditis (A52.03), syphilitic cerebral arteritis (A52.04), other cerebrovascular syphilis (A52.05), other syphilitic heart involvement (A52.06) and other cardiovascular syphilis (A52.09).

As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.

In MS-DRG v44.0, it is part of the grouping logic for DRG 314 (Other Circulatory System Diagnoses with MCC, relative weight 2.0873), DRG 315 (Other Circulatory System Diagnoses with CC, relative weight 0.9508) and DRG 316 (Other Circulatory System Diagnoses without CC/MCC, relative weight 0.6677), in MDC 05 (Diseases and Disorders of the Circulatory System), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Before ICD-10, this condition was coded in ICD-9-CM as 093.9 (cardiovascular syphilis, unspecified).