ICD-10-CM 2027 diagnosis code
B57.4Chagas' disease (chronic) with nervous system involvement
B57.4 is a header code, so it can't be reported by itself. Choose one of the 4 more specific codes beneath it.
Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About B57.4
B57.4 is the ICD-10-CM diagnosis code for Chagas' disease (chronic) with nervous system involvement. It belongs to category B57 (Chagas' disease), block B50-B64 (protozoal diseases) and chapter 1 (certain infectious and parasitic diseases). It is a header code, so it can't be reported by itself; one of its 4 subcodes must be used instead.
Within B57 (Chagas' disease), B57.4 is specifically for Chagas' disease (chronic) with nervous system involvement. Related codes cover acute Chagas' disease with heart involvement (B57.0), acute Chagas' disease without heart involvement (B57.1), (chronic) with heart involvement (B57.2), (chronic) with digestive system involvement (B57.3) and (chronic) with other organ involvement (B57.5).
To report this condition, pick the subcode that matches the documentation: B57.40 (unspecified), B57.41 (disease), B57.42 (disease) and B57.49 (disease).
It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.
Specific codes under B57.4
Notes that apply from higher levels
Instructions written at a parent level also apply to B57.4.
› From B57 Chagas' disease
- American trypanosomiasis
- infection due to Trypanosoma cruzi
Broader instructions also apply from B50-B64 Protozoal diseases and Chapter 1: Certain infectious and parasitic diseases.
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
- No changes since FY2016.
Common questions about B57.4
Is B57.4 billable?
- No. B57.4 is a header code. Report one of its more specific subcodes instead.