C26.1Malignant neoplasm of spleen

C26.1 is the ICD-10-CM diagnosis code for malignant neoplasm of spleen. It belongs to category C26 (malignant neoplasm of other and ill-defined digestive organs), block C15-C26 (malignant neoplasms of digestive organs) and chapter 2 (neoplasms). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within C26 (malignant neoplasm of other and ill-defined digestive organs), C26.1 is specifically for malignant neoplasm of spleen. Related codes cover intestinal tract, part unspecified (C26.0) and ill-defined sites within the digestive system (C26.9).

Don't report C26.1 together with the conditions in its Excludes1 note: Hodgkin lymphoma (C81.-) and non-Hodgkin lymphoma (C82-C85).

It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.

In MS-DRG v44.0, it is part of the grouping logic for DRG 820 (Lymphoma and Leukemia with Major O.R. Procedures with MCC, relative weight 6.2481), DRG 821 (Lymphoma and Leukemia with Major O.R. Procedures with CC, relative weight 2.2023), DRG 822 (Lymphoma and Leukemia with Major O.R. Procedures without CC/MCC, relative weight 1.1272), DRG 823 (Lymphoma and Non-Acute Leukemia with Other Procedures with MCC, relative weight 4.6059), DRG 824 (Lymphoma and Non-Acute Leukemia with Other Procedures with CC, relative weight 2.2515), DRG 825 (Lymphoma and Non-Acute Leukemia with Other Procedures without CC/MCC, relative weight 1.2995) and 3 more, in MDC 17 (Myeloproliferative Diseases and Disorders, Poorly Differentiated Neoplasms), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Before ICD-10, this condition was coded in ICD-9-CM as 159.1 (malignant neoplasm of spleen, not elsewhere classified).