ICD-10-CM 2027 diagnosis code
C72.22Malignant neoplasm of left olfactory nerve
C72.22 is a valid, billable ICD-10-CM code for malignant neoplasm of left olfactory nerve. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.
Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About C72.22
C72.22 is the ICD-10-CM diagnosis code for malignant neoplasm of left olfactory nerve. It belongs to category C72 (malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system), block C69-C72 (malignant neoplasms of eye, brain and other parts of central nervous system) and chapter 2 (neoplasms). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.
Within C72.2 (malignant neoplasm of olfactory nerve), C72.22 is specifically for malignant neoplasm of left olfactory nerve. Related codes cover unspecified olfactory nerve (C72.20) and right olfactory nerve (C72.21).
As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.
In MS-DRG v44.0, it is part of the grouping logic for DRG 054 (Nervous System Neoplasms with MCC, relative weight 1.5194) and DRG 055 (Nervous System Neoplasms without MCC, relative weight 1.0296), in MDC 01 (Diseases and Disorders of the Nervous System), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.
Before ICD-10, this condition was coded in ICD-9-CM as 192.0 (malignant neoplasm of cranial nerves).
Notes that apply from higher levels
Instructions written at a parent level also apply to C72.22.
› From C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
Broader instructions also apply from Chapter 2: Neoplasms.
MS-DRG v44.0 grouping
All DRGs →Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.
MDC 01 · Diseases and Disorders of the Nervous System
ICD-9-CM equivalent
Converter →- 192.0Malignant neoplasm of cranial nervesapproximate
From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
- No changes since FY2016.
Common questions about C72.22
Is C72.22 billable?
- Yes. C72.22 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can C72.22 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict C72.22 as a principal diagnosis.
Is C72.22 a CC or MCC?
- C72.22 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.
What DRG does C72.22 group to?
- C72.22 is used in the MS-DRG v44.0 logic for MS-DRG 054 (Nervous System Neoplasms with MCC) and MS-DRG 055 (Nervous System Neoplasms without MCC). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.
What is the ICD-9 code for C72.22?
- The CMS General Equivalence Mappings map C72.22 to ICD-9-CM 192.0.