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ICD-10-CM 2027 diagnosis code

C75.2Malignant neoplasm of craniopharyngeal duct

✓ Billable / specificCC — complication/comorbidity

C75.2 is a valid, billable ICD-10-CM code for malignant neoplasm of craniopharyngeal duct. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About C75.2

C75.2 is the ICD-10-CM diagnosis code for malignant neoplasm of craniopharyngeal duct. It belongs to category C75 (malignant neoplasm of other endocrine glands and related structures), block C73-C75 (malignant neoplasms of thyroid and other endocrine glands) and chapter 2 (neoplasms). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within C75 (malignant neoplasm of other endocrine glands and related structures), C75.2 is specifically for malignant neoplasm of craniopharyngeal duct. Related codes cover of parathyroid gland (C75.0), of pituitary gland (C75.1), of pineal gland (C75.3), of carotid body (C75.4), of aortic body and other paraganglia (C75.5), with pluriglandular involvement, unspecified (C75.8) and of endocrine gland, unspecified (C75.9).

As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.

In MS-DRG v44.0, it is part of the grouping logic for DRG 643 (Endocrine Disorders with MCC, relative weight 1.6139), DRG 644 (Endocrine Disorders with CC, relative weight 1.0044) and DRG 645 (Endocrine Disorders without CC/MCC, relative weight 0.7459), in MDC 10 (Endocrine, Nutritional and Metabolic Diseases and Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Before ICD-10, this condition was coded in ICD-9-CM as 194.3 (malignant neoplasm of pituitary gland and craniopharyngeal duct).

Notes that apply from higher levels

Instructions written at a parent level also apply to C75.2.

› From C75 Malignant neoplasm of other endocrine glands and related structures
Excludes1
  • malignant carcinoid tumors (C7A.0-)
  • malignant neoplasm of adrenal gland (C74.-)
  • malignant neoplasm of endocrine pancreas (C25.4)
  • malignant neoplasm of islets of Langerhans (C25.4)
  • malignant neoplasm of ovary (C56.-)
  • malignant neoplasm of testis (C62.-)
  • malignant neoplasm of thymus (C37)
  • malignant neoplasm of thyroid gland (C73)
  • malignant neuroendocrine tumors (C7A.-)

Broader instructions also apply from Chapter 2: Neoplasms.

Table of Drugs & Neoplasms entries

MS-DRG v44.0 grouping

All DRGs →

Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.

ICD-9-CM equivalent

Converter →
  • 194.3Malignant neoplasm of pituitary gland and craniopharyngeal ductapproximate

From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about C75.2

Is C75.2 billable?

Yes. C75.2 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can C75.2 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict C75.2 as a principal diagnosis.

Is C75.2 a CC or MCC?

C75.2 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.

What DRG does C75.2 group to?

C75.2 is used in the MS-DRG v44.0 logic for MS-DRG 643 (Endocrine Disorders with MCC), MS-DRG 644 (Endocrine Disorders with CC) and MS-DRG 645 (Endocrine Disorders without CC/MCC). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.

What is the ICD-9 code for C75.2?

The CMS General Equivalence Mappings map C75.2 to ICD-9-CM 194.3.