ICD-10-CM 2027 diagnosis code
C81.3Lymphocyte depleted Hodgkin lymphoma
C81.3 is a header code, so it can't be reported by itself. Choose one of the 11 more specific codes beneath it.
Code last changed in FY2017 (effective October 1, 2016). Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About C81.3
C81.3 is the ICD-10-CM diagnosis code for lymphocyte depleted Hodgkin lymphoma. It belongs to category C81 (Hodgkin lymphoma), block C81-C96 (malignant neoplasms of lymphoid, hematopoietic and related tissue) and chapter 2 (neoplasms). It is a header code, so it can't be reported by itself; one of its 11 subcodes must be used instead.
Within C81 (Hodgkin lymphoma), C81.3 is specifically for lymphocyte depleted Hodgkin lymphoma. Related codes cover nodular lymphocyte predominant Hodgkin lymphoma (C81.0), nodular sclerosis Hodgkin lymphoma (C81.1), mixed cellularity Hodgkin lymphoma (C81.2), Lymphocyte-rich Hodgkin lymphoma (C81.4), other Hodgkin lymphoma (C81.7) and unspecified (C81.9).
To report this condition, pick the subcode that matches the documentation: C81.30 (unspecified site), C81.31 (lymph nodes of head, face, and neck), C81.32 (intrathoracic lymph nodes), C81.33 (intra-abdominal lymph nodes), C81.34 (lymph nodes of axilla and upper limb), C81.35 (lymph nodes of inguinal region and lower limb), C81.36 (intrapelvic lymph nodes), C81.37 (spleen) and 3 more.
It has been part of ICD-10-CM since the code set took effect on October 1, 2015, and changed in FY2017 (title revised).
Specific codes under C81.3
- C81.30Lymphocyte depleted Hodgkin lymphoma, unspecified siteBillable
- C81.31Lymphocyte depleted Hodgkin lymphoma, lymph nodes of head, face, and neckBillable
- C81.32Lymphocyte depleted Hodgkin lymphoma, intrathoracic lymph nodesBillable
- C81.33Lymphocyte depleted Hodgkin lymphoma, intra-abdominal lymph nodesBillable
- C81.34Lymphocyte depleted Hodgkin lymphoma, lymph nodes of axilla and upper limbBillable
- C81.35Lymphocyte depleted Hodgkin lymphoma, lymph nodes of inguinal region and lower limbBillable
- C81.36Lymphocyte depleted Hodgkin lymphoma, intrapelvic lymph nodesBillable
- C81.37Lymphocyte depleted Hodgkin lymphoma, spleenBillable
- C81.38Lymphocyte depleted Hodgkin lymphoma, lymph nodes of multiple sitesBillable
- C81.39Lymphocyte depleted Hodgkin lymphoma, extranodal and solid organ sitesBillable
- C81.3ALymphocyte depleted Hodgkin lymphoma, in remissionBillable
Coding notes
- Lymphocyte depleted classical Hodgkin lymphoma
Notes that apply from higher levels
Instructions written at a parent level also apply to C81.3.
› From C81 Hodgkin lymphoma
- personal history of Hodgkin lymphoma (Z85.71)
Broader instructions also apply from C81-C96 Malignant neoplasms of lymphoid, hematopoietic and related tissue and Chapter 2: Neoplasms.
Alphabetic index entries
2 entriesTerms in the official ICD-10-CM index that lead to C81.3.
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
- FY2017 (effective 10/1/2016): Title revised — was “Lymphocyte depleted classical Hodgkin lymphoma”
Common questions about C81.3
Is C81.3 billable?
- No. C81.3 is a header code. Report one of its more specific subcodes instead.