ICD-10-CM 2027 diagnosis code
C95.0Acute leukemia of unspecified cell type
C95.0 is a header code, so it can't be reported by itself. Choose one of the 3 more specific codes beneath it.
Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About C95.0
C95.0 is the ICD-10-CM diagnosis code for acute leukemia of unspecified cell type. It belongs to category C95 (leukemia of unspecified cell type), block C81-C96 (malignant neoplasms of lymphoid, hematopoietic and related tissue) and chapter 2 (neoplasms). It is a header code, so it can't be reported by itself; one of its 3 subcodes must be used instead.
Within C95, choose C95.0 (Acute leukemia of unspecified cell type) only when documentation doesn't support a more specific option: chronic leukemia of unspecified cell type (C95.1) and leukemia, unspecified (C95.9).
To report this condition, pick the subcode that matches the documentation: C95.00 (not having achieved remission), C95.01 (in remission) and C95.02 (in relapse).
Don't report C95.0 together with the conditions in its Excludes1 note: acute exacerbation of unspecified chronic leukemia (C95.10).
It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.
Specific codes under C95.0
Coding notes
- Acute bilineal leukemia
- Acute mixed lineage leukemia
- Biphenotypic acute leukemia
- Stem cell leukemia of unclear lineage
- acute exacerbation of unspecified chronic leukemia (C95.10)
Notes that apply from higher levels
Instructions written at a parent level also apply to C95.0.
› From C95 Leukemia of unspecified cell type
- personal history of leukemia (Z85.6)
Broader instructions also apply from C81-C96 Malignant neoplasms of lymphoid, hematopoietic and related tissue and Chapter 2: Neoplasms.
Alphabetic index entries
6 entriesTerms in the official ICD-10-CM index that lead to C95.0.
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
- No changes since FY2016.
Common questions about C95.0
Is C95.0 billable?
- No. C95.0 is a header code. Report one of its more specific subcodes instead.