D25.1Intramural leiomyoma of uterus

D25.1 is the ICD-10-CM diagnosis code for Intramural leiomyoma of uterus. It belongs to category D25 (leiomyoma of uterus), block D10-D36 (benign neoplasms, except benign neuroendocrine tumors) and chapter 2 (neoplasms). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within D25 (leiomyoma of uterus), D25.1 is specifically for Intramural leiomyoma of uterus. Related codes cover submucous leiomyoma of uterus (D25.0), Subserosal leiomyoma of uterus (D25.2) and unspecified (D25.9).

It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.

In MS-DRG v44.0, it is part of the grouping logic for DRG 742 (Uterine and Adnexa Procedures for Non-Malignancy with CC/MCC, relative weight 1.8456), DRG 743 (Uterine and Adnexa Procedures for Non-Malignancy without CC/MCC, relative weight 1.2974), DRG 760 (Menstrual and Other Female Reproductive System Disorders with CC/MCC, relative weight 1.0129) and DRG 761 (Menstrual and Other Female Reproductive System Disorders without CC/MCC, relative weight 0.7041), in MDC 13 (Diseases and Disorders of the Female Reproductive System), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It is on the CMS list of diagnoses consistent only with female patients (the sex-conflict edit itself was retired in FY2025).

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Before ICD-10, this condition was coded in ICD-9-CM as 218.1 (Intramural leiomyoma of uterus).