E08.52Diabetes mellitus due to underlying condition with diabetic peripheral angiopathy with gangrene

E08.52 is the ICD-10-CM diagnosis code for diabetes mellitus due to underlying condition with diabetic peripheral angiopathy with gangrene. It belongs to category E08 (diabetes mellitus due to underlying condition), block E08-E13 (diabetes mellitus) and chapter 4 (endocrine, nutritional and metabolic diseases). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within E08.5 (diabetes mellitus due to underlying condition with circulatory complications), E08.52 is specifically for diabetes mellitus due to underlying condition with diabetic peripheral angiopathy with gangrene. Related codes cover diabetic peripheral angiopathy without gangrene (E08.51) and other circulatory complications (E08.59).

Code first the underlying condition, such as: congenital rubella (P35.0), Cushing's syndrome (E24.-), cystic fibrosis (E84.-), malignant neoplasm (C00-C96) and 2 more.

Use an additional code to identify control using: injectable non-insulin antidiabetic drugs (Z79.85), insulin (Z79.4), oral antidiabetic drugs (Z79.84) and oral hypoglycemic drugs (Z79.84).

As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.

In MS-DRG v44.0, it is part of the grouping logic for DRG 008 (Simultaneous Pancreas, Islet Cell and Kidney Transplant, relative weight 5.5146), DRG 010 (Pancreas or Islet Cell Transplant, relative weight 7.5259), DRG 019 (Simultaneous Pancreas, Islet Cell and Kidney Transplant with Hemodialysis, relative weight 7.5493), DRG 299 (Peripheral Vascular Disorders with MCC, relative weight 1.5842), DRG 300 (Peripheral Vascular Disorders with CC, relative weight 1.0464) and DRG 301 (Peripheral Vascular Disorders without CC/MCC, relative weight 0.7133), in Pre-MDC and MDC 05 (Diseases and Disorders of the Circulatory System), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It is a manifestation code, so it describes the effect of an underlying disease and can't be the principal diagnosis. Code the underlying condition first.

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Before ICD-10, this condition was coded in ICD-9-CM as 249.70 (secondary diabetes mellitus with peripheral circulatory disorders, not stated as uncontrolled, or unspecified), 443.81 (peripheral angiopathy in diseases classified elsewhere) and 785.4 (gangrene).