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ICD-10-CM 2027 diagnosis code

E10.52Type 1 diabetes mellitus with diabetic peripheral angiopathy with gangrene

✓ Billable / specificCC — complication/comorbidity

E10.52 is a valid, billable ICD-10-CM code for type 1 diabetes mellitus with diabetic peripheral angiopathy with gangrene. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.Short description: Type 1 diabetes w diabetic peripheral angiopathy w gangrene

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About E10.52

E10.52 is the ICD-10-CM diagnosis code for type 1 diabetes mellitus with diabetic peripheral angiopathy with gangrene. It belongs to category E10 (type 1 diabetes mellitus), block E08-E13 (diabetes mellitus) and chapter 4 (endocrine, nutritional and metabolic diseases). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within E10.5 (type 1 diabetes mellitus with circulatory complications), E10.52 is specifically for type 1 diabetes mellitus with diabetic peripheral angiopathy with gangrene. Related codes cover diabetic peripheral angiopathy without gangrene (E10.51) and other circulatory complications (E10.59).

As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.

In MS-DRG v44.0, it is part of the grouping logic for DRG 008 (Simultaneous Pancreas, Islet Cell and Kidney Transplant, relative weight 5.5146), DRG 010 (Pancreas or Islet Cell Transplant, relative weight 7.5259), DRG 019 (Simultaneous Pancreas, Islet Cell and Kidney Transplant with Hemodialysis, relative weight 7.5493), DRG 299 (Peripheral Vascular Disorders with MCC, relative weight 1.5842), DRG 300 (Peripheral Vascular Disorders with CC, relative weight 1.0464) and DRG 301 (Peripheral Vascular Disorders without CC/MCC, relative weight 0.7133), in Pre-MDC and MDC 05 (Diseases and Disorders of the Circulatory System), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Before ICD-10, this condition was coded in ICD-9-CM as 250.71 (diabetes with peripheral circulatory disorders, type I [juvenile type], not stated as uncontrolled), 443.81 (peripheral angiopathy in diseases classified elsewhere) and 785.4 (gangrene).

Coding notes

Applicable toConditions and synonyms classified to this code
  • Type 1 diabetes mellitus with diabetic gangrene

Notes that apply from higher levels

Instructions written at a parent level also apply to E10.52.

› From E10 Type 1 diabetes mellitus
Includes
  • brittle diabetes (mellitus)
  • diabetes (mellitus) due to autoimmune process
  • diabetes (mellitus) due to immune mediated pancreatic islet beta-cell destruction
  • idiopathic diabetes (mellitus)
  • juvenile onset diabetes (mellitus)
  • ketosis-prone diabetes (mellitus)
Excludes1
  • diabetes mellitus due to underlying condition (E08.-)
  • drug or chemical induced diabetes mellitus (E09.-)
  • gestational diabetes (O24.4-)
  • hyperglycemia NOS (R73.9)
  • neonatal diabetes mellitus (P70.2)
  • postpancreatectomy diabetes mellitus (E13.-)
  • postprocedural diabetes mellitus (E13.-)
  • secondary diabetes mellitus NEC (E13.-)
  • type 2 diabetes mellitus (E11.-)

Broader instructions also apply from Chapter 4: Endocrine, nutritional and metabolic diseases.

Alphabetic index entries

2 entries

Terms in the official ICD-10-CM index that lead to E10.52.

MS-DRG v44.0 grouping

All DRGs →

Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.

ICD-9-CM equivalent

Converter →
  • 250.71Diabetes with peripheral circulatory disorders, type I [juvenile type], not stated as uncontrolledapproximate, combination
  • 443.81Peripheral angiopathy in diseases classified elsewhereapproximate, combination
  • 785.4Gangreneapproximate, combination

From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about E10.52

Is E10.52 billable?

Yes. E10.52 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can E10.52 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict E10.52 as a principal diagnosis.

Is E10.52 a CC or MCC?

E10.52 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.

What DRG does E10.52 group to?

E10.52 is used in the MS-DRG v44.0 logic for MS-DRG 008 (Simultaneous Pancreas, Islet Cell and Kidney Transplant), MS-DRG 010 (Pancreas or Islet Cell Transplant), MS-DRG 019 (Simultaneous Pancreas, Islet Cell and Kidney Transplant with Hemodialysis), MS-DRG 299 (Peripheral Vascular Disorders with MCC), MS-DRG 300 (Peripheral Vascular Disorders with CC) and MS-DRG 301 (Peripheral Vascular Disorders without CC/MCC). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.

What is the ICD-9 code for E10.52?

The CMS General Equivalence Mappings map E10.52 to ICD-9-CM 250.71, 443.81 and 785.4.