Skip to content
Dx

ICD-10-CM 2027 diagnosis code

E10.65Type 1 diabetes mellitus with hyperglycemia

✓ Billable / specific

E10.65 is a valid, billable ICD-10-CM code for type 1 diabetes mellitus with hyperglycemia. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About E10.65

E10.65 is the ICD-10-CM diagnosis code for type 1 diabetes mellitus with hyperglycemia. It belongs to category E10 (type 1 diabetes mellitus), block E08-E13 (diabetes mellitus) and chapter 4 (endocrine, nutritional and metabolic diseases). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within E10.6 (type 1 diabetes mellitus with other specified complications), E10.65 is specifically for type 1 diabetes mellitus with hyperglycemia. Related codes cover diabetic arthropathy (E10.61), skin complications (E10.62), oral complications (E10.63), hypoglycemia (E10.64) and other specified complication (E10.69).

It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.

In MS-DRG v44.0, it is part of the grouping logic for DRG 008 (Simultaneous Pancreas, Islet Cell and Kidney Transplant, relative weight 5.5146), DRG 010 (Pancreas or Islet Cell Transplant, relative weight 7.5259), DRG 019 (Simultaneous Pancreas, Islet Cell and Kidney Transplant with Hemodialysis, relative weight 7.5493), DRG 637 (Diabetes with MCC, relative weight 1.4129), DRG 638 (Diabetes with CC, relative weight 0.9019) and DRG 639 (Diabetes without CC/MCC, relative weight 0.6376), in Pre-MDC and MDC 10 (Endocrine, Nutritional and Metabolic Diseases and Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Before ICD-10, this condition was coded in ICD-9-CM as 250.81 (diabetes with other specified manifestations, type I [juvenile type], not stated as uncontrolled).

Notes that apply from higher levels

Instructions written at a parent level also apply to E10.65.

› From E10 Type 1 diabetes mellitus
Includes
  • brittle diabetes (mellitus)
  • diabetes (mellitus) due to autoimmune process
  • diabetes (mellitus) due to immune mediated pancreatic islet beta-cell destruction
  • idiopathic diabetes (mellitus)
  • juvenile onset diabetes (mellitus)
  • ketosis-prone diabetes (mellitus)
Excludes1
  • diabetes mellitus due to underlying condition (E08.-)
  • drug or chemical induced diabetes mellitus (E09.-)
  • gestational diabetes (O24.4-)
  • hyperglycemia NOS (R73.9)
  • neonatal diabetes mellitus (P70.2)
  • postpancreatectomy diabetes mellitus (E13.-)
  • postprocedural diabetes mellitus (E13.-)
  • secondary diabetes mellitus NEC (E13.-)
  • type 2 diabetes mellitus (E11.-)

Broader instructions also apply from Chapter 4: Endocrine, nutritional and metabolic diseases.

Alphabetic index entries

1 entries

Terms in the official ICD-10-CM index that lead to E10.65.

MS-DRG v44.0 grouping

All DRGs →

Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.

MDC 10 · Endocrine, Nutritional and Metabolic Diseases and Disorders

ICD-9-CM equivalent

Converter →
  • 250.81Diabetes with other specified manifestations, type I [juvenile type], not stated as uncontrolledapproximate

From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about E10.65

Is E10.65 billable?

Yes. E10.65 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can E10.65 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict E10.65 as a principal diagnosis.

Is E10.65 a CC or MCC?

No. E10.65 is neither a CC nor an MCC under MS-DRG v44.0.

What DRG does E10.65 group to?

E10.65 is used in the MS-DRG v44.0 logic for MS-DRG 008 (Simultaneous Pancreas, Islet Cell and Kidney Transplant), MS-DRG 010 (Pancreas or Islet Cell Transplant), MS-DRG 019 (Simultaneous Pancreas, Islet Cell and Kidney Transplant with Hemodialysis), MS-DRG 637 (Diabetes with MCC), MS-DRG 638 (Diabetes with CC) and MS-DRG 639 (Diabetes without CC/MCC). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.

What is the ICD-9 code for E10.65?

The CMS General Equivalence Mappings map E10.65 to ICD-9-CM 250.81.