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ICD-10-CM 2027 diagnosis code

E11.49Type 2 diabetes mellitus with other diabetic neurological complication

✓ Billable / specific

E11.49 is a valid, billable ICD-10-CM code for type 2 diabetes mellitus with other diabetic neurological complication. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.Short description: Type 2 diabetes w oth diabetic neurological complication

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About E11.49

E11.49 is the ICD-10-CM diagnosis code for type 2 diabetes mellitus with other diabetic neurological complication. It belongs to category E11 (type 2 diabetes mellitus), block E08-E13 (diabetes mellitus) and chapter 4 (endocrine, nutritional and metabolic diseases). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within E11.4, choose E11.49 (other diabetic neurological complication) only when documentation doesn't support a more specific option: diabetic neuropathy, unspecified (E11.40), diabetic mononeuropathy (E11.41), diabetic polyneuropathy (E11.42), diabetic autonomic (poly)neuropathy (E11.43) and diabetic amyotrophy (E11.44).

Use an additional code to identify control using: injectable non-insulin antidiabetic drugs (Z79.85), insulin (Z79.4), oral antidiabetic drugs (Z79.84) and oral hypoglycemic drugs (Z79.84).

It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.

In MS-DRG v44.0, it is part of the grouping logic for DRG 008 (Simultaneous Pancreas, Islet Cell and Kidney Transplant, relative weight 5.5146), DRG 010 (Pancreas or Islet Cell Transplant, relative weight 7.5259), DRG 019 (Simultaneous Pancreas, Islet Cell and Kidney Transplant with Hemodialysis, relative weight 7.5493), DRG 073 (Cranial and Peripheral Nerve Disorders with MCC, relative weight 1.5779) and DRG 074 (Cranial and Peripheral Nerve Disorders without MCC, relative weight 1.0173), in Pre-MDC and MDC 01 (Diseases and Disorders of the Nervous System), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Before ICD-10, this condition was coded in ICD-9-CM as 250.60 (diabetes with neurological manifestations, type II or unspecified type, not stated as uncontrolled), 250.60 (diabetes with neurological manifestations, type II or unspecified type, not stated as uncontrolled) and 349.89 (other specified disorders of nervous system).

Notes that apply from higher levels

Instructions written at a parent level also apply to E11.49.

› From E11 Type 2 diabetes mellitus
Includes
  • diabetes (mellitus) due to insulin secretory defect
  • diabetes NOS
  • insulin resistant diabetes (mellitus)
Excludes1
  • diabetes mellitus due to underlying condition (E08.-)
  • drug or chemical induced diabetes mellitus (E09.-)
  • gestational diabetes (O24.4-)
  • neonatal diabetes mellitus (P70.2)
  • postpancreatectomy diabetes mellitus (E13.-)
  • postprocedural diabetes mellitus (E13.-)
  • secondary diabetes mellitus NEC (E13.-)
  • type 1 diabetes mellitus (E10.-)
Use additional code
  • code to identify control using:
  • injectable non-insulin antidiabetic drugs (Z79.85)
  • insulin (Z79.4)
  • oral antidiabetic drugs (Z79.84)
  • oral hypoglycemic drugs (Z79.84)

Broader instructions also apply from Chapter 4: Endocrine, nutritional and metabolic diseases.

Alphabetic index entries

2 entries

Terms in the official ICD-10-CM index that lead to E11.49.

MS-DRG v44.0 grouping

All DRGs →

Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.

ICD-9-CM equivalent

Converter →
  • 250.60Diabetes with neurological manifestations, type II or unspecified type, not stated as uncontrolledapproximate
  • 250.60Diabetes with neurological manifestations, type II or unspecified type, not stated as uncontrolledapproximate, combination
  • 349.89Other specified disorders of nervous systemapproximate, combination

From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about E11.49

Is E11.49 billable?

Yes. E11.49 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can E11.49 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict E11.49 as a principal diagnosis.

Is E11.49 a CC or MCC?

No. E11.49 is neither a CC nor an MCC under MS-DRG v44.0.

What DRG does E11.49 group to?

E11.49 is used in the MS-DRG v44.0 logic for MS-DRG 008 (Simultaneous Pancreas, Islet Cell and Kidney Transplant), MS-DRG 010 (Pancreas or Islet Cell Transplant), MS-DRG 019 (Simultaneous Pancreas, Islet Cell and Kidney Transplant with Hemodialysis), MS-DRG 073 (Cranial and Peripheral Nerve Disorders with MCC) and MS-DRG 074 (Cranial and Peripheral Nerve Disorders without MCC). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.

What is the ICD-9 code for E11.49?

The CMS General Equivalence Mappings map E11.49 to ICD-9-CM 250.60, 250.60 and 349.89.