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ICD-10-CM 2027 diagnosis code

E11.641Type 2 diabetes mellitus with hypoglycemia with coma

E11.641 is a valid, billable ICD-10-CM code for type 2 diabetes mellitus with hypoglycemia with coma. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About E11.641

E11.641 is the ICD-10-CM diagnosis code for type 2 diabetes mellitus with hypoglycemia with coma. It belongs to category E11 (type 2 diabetes mellitus), block E08-E13 (diabetes mellitus) and chapter 4 (endocrine, nutritional and metabolic diseases). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within E11.64 (type 2 diabetes mellitus with hypoglycemia), E11.641 is specifically for type 2 diabetes mellitus with hypoglycemia with coma. Related codes cover without coma (E11.649).

Use an additional code to identify control using: injectable non-insulin antidiabetic drugs (Z79.85), insulin (Z79.4), oral antidiabetic drugs (Z79.84) and oral hypoglycemic drugs (Z79.84).

As a secondary diagnosis it is an MCC (major complication or comorbidity), which can move an inpatient stay into the highest-paying "with MCC" MS-DRG of its family, unless the principal diagnosis excludes it.

In MS-DRG v44.0, it is part of the grouping logic for DRG 008 (Simultaneous Pancreas, Islet Cell and Kidney Transplant, relative weight 5.5146), DRG 010 (Pancreas or Islet Cell Transplant, relative weight 7.5259), DRG 019 (Simultaneous Pancreas, Islet Cell and Kidney Transplant with Hemodialysis, relative weight 7.5493), DRG 637 (Diabetes with MCC, relative weight 1.4129), DRG 638 (Diabetes with CC, relative weight 0.9019) and DRG 639 (Diabetes without CC/MCC, relative weight 0.6376), in Pre-MDC and MDC 10 (Endocrine, Nutritional and Metabolic Diseases and Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Before ICD-10, this condition was coded in ICD-9-CM as 250.30 (diabetes with other coma, type II or unspecified type, not stated as uncontrolled).

Notes that apply from higher levels

Instructions written at a parent level also apply to E11.641.

› From E11.64 Type 2 diabetes mellitus with hypoglycemia
Use additional code
  • code for hypoglycemia level, if applicable (E16.A-)
› From E11 Type 2 diabetes mellitus
Includes
  • diabetes (mellitus) due to insulin secretory defect
  • diabetes NOS
  • insulin resistant diabetes (mellitus)
Excludes1
  • diabetes mellitus due to underlying condition (E08.-)
  • drug or chemical induced diabetes mellitus (E09.-)
  • gestational diabetes (O24.4-)
  • neonatal diabetes mellitus (P70.2)
  • postpancreatectomy diabetes mellitus (E13.-)
  • postprocedural diabetes mellitus (E13.-)
  • secondary diabetes mellitus NEC (E13.-)
  • type 1 diabetes mellitus (E10.-)
Use additional code
  • code to identify control using:
  • injectable non-insulin antidiabetic drugs (Z79.85)
  • insulin (Z79.4)
  • oral antidiabetic drugs (Z79.84)
  • oral hypoglycemic drugs (Z79.84)

Broader instructions also apply from Chapter 4: Endocrine, nutritional and metabolic diseases.

Alphabetic index entries

4 entries

Terms in the official ICD-10-CM index that lead to E11.641.

MS-DRG v44.0 grouping

All DRGs →

Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.

ICD-9-CM equivalent

Converter →
  • 250.30Diabetes with other coma, type II or unspecified type, not stated as uncontrolledapproximate

From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about E11.641

Is E11.641 billable?

Yes. E11.641 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can E11.641 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict E11.641 as a principal diagnosis.

Is E11.641 a CC or MCC?

E11.641 is an MCC (major complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.

What DRG does E11.641 group to?

E11.641 is used in the MS-DRG v44.0 logic for MS-DRG 008 (Simultaneous Pancreas, Islet Cell and Kidney Transplant), MS-DRG 010 (Pancreas or Islet Cell Transplant), MS-DRG 019 (Simultaneous Pancreas, Islet Cell and Kidney Transplant with Hemodialysis), MS-DRG 637 (Diabetes with MCC), MS-DRG 638 (Diabetes with CC) and MS-DRG 639 (Diabetes without CC/MCC). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.

What is the ICD-9 code for E11.641?

The CMS General Equivalence Mappings map E11.641 to ICD-9-CM 250.30.