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ICD-10-CM 2027 diagnosis code

F06.3Mood disorder due to known physiological condition

Not billable — use a more specific code

F06.3 is a header code, so it can't be reported by itself. Choose one of the 5 more specific codes beneath it.

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About F06.3

F06.3 is the ICD-10-CM diagnosis code for mood disorder due to known physiological condition. It belongs to category F06 (other mental disorders due to known physiological condition), block F01-F09 (mental disorders due to known physiological conditions) and chapter 5 (mental, Behavioral and Neurodevelopmental disorders). It is a header code, so it can't be reported by itself; one of its 5 subcodes must be used instead.

Within F06 (other mental disorders due to known physiological condition), F06.3 is specifically for mood disorder due to known physiological condition. Related codes cover psychotic disorder with hallucinations due to known physiological condition (F06.0), Catatonic disorder due to known physiological condition (F06.1), psychotic disorder with delusions due to known physiological condition (F06.2), anxiety disorder due to known physiological condition (F06.4), mild neurocognitive disorder due to known physiological condition (F06.7) and other specified mental disorders due to known physiological condition (F06.8).

To report this condition, pick the subcode that matches the documentation: F06.30 (unspecified), F06.31 (with depressive features), F06.32 (with major depressive-like episode), F06.33 (with manic features) and F06.34 (with mixed features).

The conditions in its Excludes2 note aren't part of F06.3, but may be coded alongside it if the patient has both: mood disorders due to alcohol and other psychoactive substances (F10-F19 with .14, .24, .94) and mood disorders, not due to known physiological condition or unspecified (F30-F39).

Code first: the underlying physiological condition.

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Specific codes under F06.3

Coding notes

Excludes2Not included here — may be reported together if both conditions exist
  • mood disorders due to alcohol and other psychoactive substances (F10-F19 with .14, .24, .94)
  • mood disorders, not due to known physiological condition or unspecified (F30-F39)

Notes that apply from higher levels

Instructions written at a parent level also apply to F06.3.

› From F06 Other mental disorders due to known physiological condition
Includes
  • mental disorders due to endocrine disorder
  • mental disorders due to exogenous hormone
  • mental disorders due to exogenous toxic substance
  • mental disorders due to primary cerebral disease
  • mental disorders due to somatic illness
  • mental disorders due to systemic disease affecting the brain
Excludes1
  • unspecified dementia (F03.-)
Excludes2
  • delirium due to known physiological condition (F05)
  • dementia as classified in F01-F02
  • other mental disorders associated with alcohol and other psychoactive substances (F10-F19)
Code first
  • the underlying physiological condition

Broader instructions also apply from F01-F09 Mental disorders due to known physiological conditions and Chapter 5: Mental, Behavioral and Neurodevelopmental disorders.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about F06.3

Is F06.3 billable?

No. F06.3 is a header code. Report one of its more specific subcodes instead.