F11.22Opioid dependence with intoxication

F11.22 is the ICD-10-CM diagnosis code for opioid dependence with intoxication. It belongs to category F11 (opioid related disorders), block F10-F19 (mental and behavioral disorders due to psychoactive substance use) and chapter 5 (mental, Behavioral and Neurodevelopmental disorders). It is a header code, so it can't be reported by itself; one of its 4 subcodes must be used instead.

Within F11.2 (opioid dependence), F11.22 is specifically for opioid dependence with intoxication. Related codes cover uncomplicated (F11.20), in remission (F11.21), with withdrawal (F11.23), with opioid-induced mood disorder (F11.24), with opioid-induced psychotic disorder (F11.25), with other opioid-induced disorder (F11.28) and with unspecified opioid-induced disorder (F11.29).

To report this condition, pick the subcode that matches the documentation: F11.220 (uncomplicated), F11.221 (delirium), F11.222 (with perceptual disturbance) and F11.229 (unspecified).

Don't report F11.22 together with the conditions in its Excludes1 note: opioid dependence with withdrawal (F11.23).

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.