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ICD-10-CM 2027 diagnosis code

G93.45Developmental and epileptic encephalopathy

✓ Billable / specificCC — complication/comorbidity

G93.45 is a valid, billable ICD-10-CM code for developmental and epileptic encephalopathy. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.

Code last changed in FY2025 (effective October 1, 2024). Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About G93.45

G93.45 is the ICD-10-CM diagnosis code for developmental and epileptic encephalopathy. It belongs to category G93 (other disorders of brain), block G89-G99 (other disorders of the nervous system) and chapter 6 (diseases of the nervous system). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within G93.4 (other and unspecified encephalopathy), G93.45 is specifically for developmental and epileptic encephalopathy. Related codes cover encephalopathy, unspecified (G93.40), metabolic encephalopathy (G93.41), Megalencephalic leukoencephalopathy with subcortical cysts (G93.42), leukoencephalopathy with calcifications and cysts (G93.43), Adult-onset leukodystrophy with axonal spheroids (G93.44) and other encephalopathy (G93.49).

As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.

In MS-DRG v44.0, it is part of the grouping logic for DRG 070 (Other Cerebrovascular Disorders with MCC, relative weight 1.6093), DRG 071 (Other Cerebrovascular Disorders with CC, relative weight 1.0177), DRG 072 (Other Cerebrovascular Disorders without CC/MCC, relative weight 0.7348), DRG 974 (HIV with Major Related Condition with MCC, relative weight 3.0506), DRG 975 (HIV with Major Related Condition with CC, relative weight 1.3252) and DRG 976 (HIV with Major Related Condition without CC/MCC, relative weight 0.8124), in MDC 01 (Diseases and Disorders of the Nervous System) and MDC 25 (Human Immunodeficiency Virus Infections), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It was added in FY2025, effective October 1, 2024.

Coding notes

Applicable toConditions and synonyms classified to this code
  • Early infantile epileptic encephalopathy
Code alsoTwo codes may be needed; sequencing depends on circumstances
  • , if applicable, associated disorders such as:
  • developmental disorders of scholastic skills (F81.-)
  • developmental disorder of speech and language (F80.-)
  • epilepsy, by specific type (G40.-)
  • intellectual disabilities (F70-F79)
  • other neurodevelopmental disorder (F88)
  • pervasive developmental disorders (F84.-)

Notes that apply from higher levels

Instructions written at a parent level also apply to G93.45.

› From G93.4 Other and unspecified encephalopathy
Excludes2
  • alcoholic encephalopathy (G31.2)
  • encephalopathy in diseases classified elsewhere (G94)
  • hypertensive encephalopathy (I67.4)
  • toxic (metabolic) encephalopathy (G92.8)

Broader instructions also apply from Chapter 6: Diseases of the nervous system.

Alphabetic index entries

2 entries

Terms in the official ICD-10-CM index that lead to G93.45.

Codes whose notes reference G93.45

MS-DRG v44.0 grouping

All DRGs →

Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2025 (effective 10/1/2024): Added
  • No changes since FY2025.

Common questions about G93.45

Is G93.45 billable?

Yes. G93.45 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can G93.45 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict G93.45 as a principal diagnosis.

Is G93.45 a CC or MCC?

G93.45 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.

What DRG does G93.45 group to?

G93.45 is used in the MS-DRG v44.0 logic for MS-DRG 070 (Other Cerebrovascular Disorders with MCC), MS-DRG 071 (Other Cerebrovascular Disorders with CC), MS-DRG 072 (Other Cerebrovascular Disorders without CC/MCC), MS-DRG 974 (HIV with Major Related Condition with MCC), MS-DRG 975 (HIV with Major Related Condition with CC) and MS-DRG 976 (HIV with Major Related Condition without CC/MCC). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.