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ICD-10-CM 2027 diagnosis code

I25.81Atherosclerosis of other coronary vessels without angina pectoris

Not billable — use a more specific code

I25.81 is a header code, so it can't be reported by itself. Choose one of the 3 more specific codes beneath it.Short description: Atherosclerosis of oth coronary vessels w/o angina pectoris

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About I25.81

I25.81 is the ICD-10-CM diagnosis code for atherosclerosis of other coronary vessels without angina pectoris. It belongs to category I25 (chronic ischemic heart disease), block I20-I25 (ischemic heart diseases) and chapter 9 (diseases of the circulatory system). It is a header code, so it can't be reported by itself; one of its 3 subcodes must be used instead.

Within I25.8, choose I25.81 (Atherosclerosis of other coronary vessels without angina pectoris) only when documentation doesn't support a more specific option: chronic total occlusion of coronary artery (I25.82), coronary atherosclerosis due to lipid rich plaque (I25.83), coronary atherosclerosis due to calcified coronary lesion (I25.84), chronic coronary microvascular dysfunction (I25.85) and other forms of chronic ischemic heart disease (I25.89).

To report this condition, pick the subcode that matches the documentation: I25.810 (pectoris), I25.811 (pectoris) and I25.812 (pectoris).

The conditions in its Excludes2 note aren't part of I25.81, but may be coded alongside it if the patient has both: atherosclerotic heart disease of native coronary artery without angina pectoris (I25.10).

Use an additional code, if applicable, to identify: coronary atherosclerosis due to calcified coronary lesion (I25.84) and coronary atherosclerosis due to lipid rich plaque (I25.83). Use an additional code to identify: chronic total occlusion of coronary artery (I25.82), exposure to environmental tobacco smoke (Z77.22), history of tobacco dependence (Z87.891), occupational exposure to environmental tobacco smoke (Z57.31), tobacco dependence (F17.-) and 1 more.

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Specific codes under I25.81

Coding notes

Excludes2Not included here — may be reported together if both conditions exist
  • atherosclerotic heart disease of native coronary artery without angina pectoris (I25.10)
Use additional codeAdd a secondary code to fully describe the condition
  • code, if applicable, to identify:
  • coronary atherosclerosis due to calcified coronary lesion (I25.84)
  • coronary atherosclerosis due to lipid rich plaque (I25.83)

Notes that apply from higher levels

Instructions written at a parent level also apply to I25.81.

› From I25 Chronic ischemic heart disease
Excludes2
  • non-ischemic myocardial injury (I5A)
Use additional code
  • code to identify:
  • chronic total occlusion of coronary artery (I25.82)
  • exposure to environmental tobacco smoke (Z77.22)
  • history of tobacco dependence (Z87.891)
  • occupational exposure to environmental tobacco smoke (Z57.31)
  • tobacco dependence (F17.-)
  • tobacco use (Z72.0)

Broader instructions also apply from I20-I25 Ischemic heart diseases and Chapter 9: Diseases of the circulatory system.

Codes whose notes reference I25.81

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about I25.81

Is I25.81 billable?

No. I25.81 is a header code. Report one of its more specific subcodes instead.