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ICD-10-CM 2027 diagnosis code

I67.3Progressive vascular leukoencephalopathy

✓ Billable / specificCC — complication/comorbidity

I67.3 is a valid, billable ICD-10-CM code for progressive vascular leukoencephalopathy. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.

Looking up by condition? See ICD-10 code for Binswanger's disease.

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About I67.3

I67.3 is the ICD-10-CM diagnosis code for progressive vascular leukoencephalopathy. It belongs to category I67 (other cerebrovascular diseases), block I60-I69 (cerebrovascular diseases) and chapter 9 (diseases of the circulatory system). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within I67 (other cerebrovascular diseases), I67.3 is specifically for progressive vascular leukoencephalopathy. Related codes cover dissection of cerebral arteries, nonruptured (I67.0), cerebral aneurysm, nonruptured (I67.1), cerebral atherosclerosis (I67.2), hypertensive encephalopathy (I67.4), Moyamoya disease (I67.5), nonpyogenic thrombosis of intracranial venous system (I67.6), cerebral arteritis, not elsewhere classified (I67.7), other specified cerebrovascular diseases (I67.8) and 1 more.

As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.

In MS-DRG v44.0, it is part of the grouping logic for DRG 056 (Degenerative Nervous System Disorders with MCC, relative weight 2.2655), DRG 057 (Degenerative Nervous System Disorders without MCC, relative weight 1.2838), DRG 974 (HIV with Major Related Condition with MCC, relative weight 3.0506), DRG 975 (HIV with Major Related Condition with CC, relative weight 1.3252) and DRG 976 (HIV with Major Related Condition without CC/MCC, relative weight 0.8124), in MDC 01 (Diseases and Disorders of the Nervous System) and MDC 25 (Human Immunodeficiency Virus Infections), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Before ICD-10, this condition was coded in ICD-9-CM as 046.3 (progressive multifocal leukoencephalopathy).

Coding notes

Applicable toConditions and synonyms classified to this code
  • Binswanger's disease

Notes that apply from higher levels

Instructions written at a parent level also apply to I67.3.

› From I67 Other cerebrovascular diseases
Excludes1
  • Occlusion and stenosis of cerebral artery causing cerebral infarction (I63.3-I63.5-)
  • Occlusion and stenosis of precerebral artery causing cerebral infarction (I63.2-)
Excludes2
  • sequelae of the listed conditions (I69.8)

Broader instructions also apply from I60-I69 Cerebrovascular diseases and Chapter 9: Diseases of the circulatory system.

Alphabetic index entries

3 entries

Terms in the official ICD-10-CM index that lead to I67.3.

MS-DRG v44.0 grouping

All DRGs →

Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.

ICD-9-CM equivalent

Converter →
  • 046.3Progressive multifocal leukoencephalopathyapproximate

From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about I67.3

Is I67.3 billable?

Yes. I67.3 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can I67.3 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict I67.3 as a principal diagnosis.

Is I67.3 a CC or MCC?

I67.3 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.

What DRG does I67.3 group to?

I67.3 is used in the MS-DRG v44.0 logic for MS-DRG 056 (Degenerative Nervous System Disorders with MCC), MS-DRG 057 (Degenerative Nervous System Disorders without MCC), MS-DRG 974 (HIV with Major Related Condition with MCC), MS-DRG 975 (HIV with Major Related Condition with CC) and MS-DRG 976 (HIV with Major Related Condition without CC/MCC). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.

What is the ICD-9 code for I67.3?

The CMS General Equivalence Mappings map I67.3 to ICD-9-CM 046.3.