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ICD-10-CM 2027 diagnosis code

J45.41Moderate persistent asthma with (acute) exacerbation

✓ Billable / specificCC — complication/comorbidity

J45.41 is a valid, billable ICD-10-CM code for moderate persistent asthma with (acute) exacerbation. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About J45.41

J45.41 is the ICD-10-CM diagnosis code for moderate persistent asthma with (acute) exacerbation. It belongs to category J45 (asthma), block J40-J4B (chronic lower respiratory diseases) and chapter 10 (diseases of the respiratory system). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within J45.4 (moderate persistent asthma), J45.41 is specifically for moderate persistent asthma with (acute) exacerbation. Related codes cover uncomplicated (J45.40) and with status asthmaticus (J45.42).

Use an additional code to identify: eosinophilic asthma (J82.83), exposure to environmental tobacco smoke (Z77.22), exposure to tobacco smoke in the perinatal period (P96.81), history of tobacco dependence (Z87.891), occupational exposure to environmental tobacco smoke (Z57.31) and 2 more.

As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.

In MS-DRG v44.0, it is part of the grouping logic for DRG 202 (Bronchitis and Asthma with CC/MCC, relative weight 0.9474) and DRG 203 (Bronchitis and Asthma without CC/MCC, relative weight 0.6512), in MDC 04 (Diseases and Disorders of the Respiratory System), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Before ICD-10, this condition was coded in ICD-9-CM as 493.02 (extrinsic asthma with (acute) exacerbation) and 493.12 (intrinsic asthma with (acute) exacerbation).

Notes that apply from higher levels

Instructions written at a parent level also apply to J45.41.

› From J45 Asthma
Includes
  • allergic (predominantly) asthma
  • allergic bronchitis NOS
  • allergic rhinitis with asthma
  • atopic asthma
  • extrinsic allergic asthma
  • hay fever with asthma
  • idiosyncratic asthma
  • intrinsic nonallergic asthma
  • nonallergic asthma
Excludes1
Excludes2
  • asthma with chronic obstructive pulmonary disease (J44.89)
  • chronic asthmatic (obstructive) bronchitis (J44.89)
  • chronic obstructive asthma (J44.89)
  • other specified chronic obstructive pulmonary disease (J44.89)
Use additional code
  • code to identify:
  • eosinophilic asthma (J82.83)
  • exposure to environmental tobacco smoke (Z77.22)
  • exposure to tobacco smoke in the perinatal period (P96.81)
  • history of tobacco dependence (Z87.891)
  • occupational exposure to environmental tobacco smoke (Z57.31)
  • tobacco dependence (F17.-)
  • tobacco use (Z72.0)

Broader instructions also apply from J40-J4B Chronic lower respiratory diseases and Chapter 10: Diseases of the respiratory system.

Alphabetic index entries

2 entries

Terms in the official ICD-10-CM index that lead to J45.41.

MS-DRG v44.0 grouping

All DRGs →

Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.

ICD-9-CM equivalent

Converter →
  • 493.02Extrinsic asthma with (acute) exacerbationapproximate
  • 493.12Intrinsic asthma with (acute) exacerbationapproximate

From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about J45.41

Is J45.41 billable?

Yes. J45.41 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can J45.41 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict J45.41 as a principal diagnosis.

Is J45.41 a CC or MCC?

J45.41 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.

What DRG does J45.41 group to?

J45.41 is used in the MS-DRG v44.0 logic for MS-DRG 202 (Bronchitis and Asthma with CC/MCC) and MS-DRG 203 (Bronchitis and Asthma without CC/MCC). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.

What is the ICD-9 code for J45.41?

The CMS General Equivalence Mappings map J45.41 to ICD-9-CM 493.02 and 493.12.