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ICD-10-CM 2027 diagnosis code

K52.22Food protein-induced enteropathy

✓ Billable / specific

K52.22 is a valid, billable ICD-10-CM code for food protein-induced enteropathy. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.

Code last changed in FY2017 (effective October 1, 2016). Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About K52.22

K52.22 is the ICD-10-CM diagnosis code for food protein-induced enteropathy. It belongs to category K52 (other and unspecified noninfective gastroenteritis and colitis), block K50-K52 (noninfective enteritis and colitis) and chapter 11 (diseases of the digestive system). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within K52.2 (allergic and dietetic gastroenteritis and colitis), K52.22 is specifically for food protein-induced enteropathy. Related codes cover food protein-induced enterocolitis syndrome (K52.21) and other allergic and dietetic gastroenteritis and colitis (K52.29).

It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.

In MS-DRG v44.0, it is part of the grouping logic for DRG 391 (Esophagitis, Gastroenteritis and Miscellaneous Digestive Disorders with MCC, relative weight 1.2392) and DRG 392 (Esophagitis, Gastroenteritis and Miscellaneous Digestive Disorders without MCC, relative weight 0.7645), in MDC 06 (Diseases and Disorders of the Digestive System), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It was added in FY2017, effective October 1, 2016.

Before ICD-10, this condition was coded in ICD-9-CM as 558.3 (allergic gastroenteritis and colitis).

Notes that apply from higher levels

Instructions written at a parent level also apply to K52.22.

› From K52.2 Allergic and dietetic gastroenteritis and colitis
Excludes2
  • allergic eosinophilic colitis (K52.82)
  • allergic eosinophilic esophagitis (K20.0)
  • allergic eosinophilic gastritis (K52.81)
  • allergic eosinophilic gastroenteritis (K52.81)
Use additional code

Broader instructions also apply from K50-K52 Noninfective enteritis and colitis and Chapter 11: Diseases of the digestive system.

Alphabetic index entries

4 entries

Terms in the official ICD-10-CM index that lead to K52.22.

Codes whose notes reference K52.22

MS-DRG v44.0 grouping

All DRGs →

Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.

ICD-9-CM equivalent

Converter →
  • 558.3Allergic gastroenteritis and colitisapproximate

From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2017 (effective 10/1/2016): Added
  • No changes since FY2017.

Common questions about K52.22

Is K52.22 billable?

Yes. K52.22 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can K52.22 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict K52.22 as a principal diagnosis.

Is K52.22 a CC or MCC?

No. K52.22 is neither a CC nor an MCC under MS-DRG v44.0.

What DRG does K52.22 group to?

K52.22 is used in the MS-DRG v44.0 logic for MS-DRG 391 (Esophagitis, Gastroenteritis and Miscellaneous Digestive Disorders with MCC) and MS-DRG 392 (Esophagitis, Gastroenteritis and Miscellaneous Digestive Disorders without MCC). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.

What is the ICD-9 code for K52.22?

The CMS General Equivalence Mappings map K52.22 to ICD-9-CM 558.3.