ICD-10-CM 2027 diagnosis code
M25.4Effusion of joint
M25.4 is a header code, so it can't be reported by itself. Choose one of the 9 more specific codes beneath it.
Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About M25.4
M25.4 is the ICD-10-CM diagnosis code for effusion of joint. It belongs to category M25 (other joint disorder, not elsewhere classified), block M20-M25 (other joint disorders) and chapter 13 (diseases of the musculoskeletal system and connective tissue). It is a header code, so it can't be reported by itself; one of its 9 subcodes must be used instead.
Within M25 (other joint disorder, not elsewhere classified), M25.4 is specifically for effusion of joint. Related codes cover Hemarthrosis (M25.0), fistula of joint (M25.1), Flail joint (M25.2), other instability of joint (M25.3), pain in joint (M25.5), Stiffness of joint, not elsewhere classified (M25.6), Osteophyte (M25.7), other specified joint disorders (M25.8) and 1 more.
To report this condition, pick the subcode that matches the documentation: M25.40 (joint), M25.41 (shoulder), M25.42 (elbow), M25.43 (wrist), M25.44 (hand), M25.45 (hip), M25.46 (knee), M25.47 (foot) and 1 more.
Don't report M25.4 together with the conditions in its Excludes1 note: hydrarthrosis in yaws (A66.6), intermittent hydrarthrosis (M12.4-) and other infective (teno)synovitis (M65.1-).
It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.
Specific codes under M25.4
Coding notes
Notes that apply from higher levels
Instructions written at a parent level also apply to M25.4.
Broader instructions also apply from M20-M25 Other joint disorders and Chapter 13: Diseases of the musculoskeletal system and connective tissue.
Codes whose notes reference M25.4
- R22Excludes1
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
- No changes since FY2016.
Common questions about M25.4
Is M25.4 billable?
- No. M25.4 is a header code. Report one of its more specific subcodes instead.