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ICD-10-CM 2027 diagnosis code

M45Ankylosing spondylitis

Not billable — use a more specific code

M45 is a header code, so it can't be reported by itself. Choose one of the 11 more specific codes beneath it.

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About M45

M45 is the ICD-10-CM diagnosis code for ankylosing spondylitis. It belongs to block M45-M49 (spondylopathies) and chapter 13 (diseases of the musculoskeletal system and connective tissue). It is a header code, so it can't be reported by itself; one of its 11 subcodes must be used instead.

To report this condition, pick the subcode that matches the documentation: M45.0 (of multiple sites in spine), M45.1 (of occipito-atlanto-axial region), M45.2 (of cervical region), M45.3 (of cervicothoracic region), M45.4 (of thoracic region), M45.5 (of thoracolumbar region), M45.6 (lumbar region), M45.7 (of lumbosacral region) and 3 more.

Don't report M45 together with the conditions in its Excludes1 note: arthropathy in Reiter's disease (M02.3-) and juvenile (ankylosing) spondylitis (M08.1).

The conditions in its Excludes2 note aren't part of M45, but may be coded alongside it if the patient has both: Behçet's disease (M35.2).

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Specific codes under M45

Coding notes

Applicable toConditions and synonyms classified to this code
  • Rheumatoid arthritis of spine
Excludes1Not coded here — never report together with this code
  • arthropathy in Reiter's disease (M02.3-)
  • juvenile (ankylosing) spondylitis (M08.1)
Excludes2Not included here — may be reported together if both conditions exist
  • Behçet's disease (M35.2)

Notes that apply from higher levels

Instructions written at a parent level also apply to M45.

Codes whose notes reference M45

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about M45

Is M45 billable?

No. M45 is a header code. Report one of its more specific subcodes instead.